ArticleNature2021
Actin cables and comet tails organize mitochondrial networks in mitosis.
Open access · greenAbstract read
In one paragraph
Article in Nature, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 110 papers.
0numbers the graph read from it
0cells of the map it votes in
110citing papers in PubMed
14.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
110 citing papers in PubMed, 186 citations in OpenAlex.
- OpticalFlow3D - a tool for measuring amorphous motion in three-dimensional fluorescence microscopy images.Journal of cell science · 2026Article
- Form and function of actin impacts actin health and aging.iScience · 2026Article
- Specialized cortical ER architecture modulates CaiScience · 2026Article
- MSTO1 functions as a TRiC assembly factor linking cytosolic proteostasis to mitochondrial function.bioRxiv : the preprint server for biology · 2026Article
- Adapting upright light sheet fluorescence microscopy for imaging at air-liquid interface.Npj imaging · 2026Article
- Mitotic Cdc42 waves encode PI(3,4)PScience advances · 2026Article
- Dynamic Proximity Networks of Myosin-19 (Myo19) and its Mitochondrial Receptors Miro2 and Metaxin-3.Molecular & cellular proteomics : MCP · 2026Article
- Chromatin- and actin-mediated mitochondrial streaming leads to patterning of mitochondrial distribution in oocytes.Nature communications · 2026Article
- RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells.FEBS open bio · 2026Article
- Non-muscle tropomyosins inhibit myosin-19 and dynamically localize to mitochondrially associated actin filaments.The Journal of biological chemistry · 2026Article
- A pore-forming toxin initiates ABI1 complex switching to promote bacterial cell-to-cell spread.Nature communications · 2026Article
- Adapting Upright Light Sheet Fluorescence Microscopy for Imaging at Air-Liquid Interface.bioRxiv : the preprint server for biology · 2026Article
- Estimating physical conditions supporting gradients of ATP concentration in the eukaryotic cell.Biophysical journal · 2026Article
- A neural network for long-term super-resolution imaging of live cells with reliable confidence quantification.Nature biotechnology · 2026Article
- Intracrine FFA4 signaling controls lipolysis at lipid droplets.Nature chemical biology · 2026Article
- Mitotic errors as triggers of cell death and inflammation.Nature cell biology · 2026Review
- Macrophage Actin Cytoskeleton in Chronic Rejection.Results and problems in cell differentiation · 2026Review
- Unequal mitochondrial segregation promotes asymmetric fates during neurogenesis.Nature communications · 2025Article
- When two worlds collide: actin dynamics on endomembranes regulates membrane trafficking.Current opinion in cell biology · 2025Review
- Bioenergetic responses to β-adrenergic stimulation in beige adipocyte depend on actomyosin driven forces.bioRxiv : the preprint server for biology · 2025Article
50 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
14 authors at 4 institutions in 2 countries.
Andrew S MooreDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Stephen M CosciaDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0002-4113-8802
Cory L SimpsonDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.
Fabian E OrtegaDepartment of Biochemistry, Stanford University, Stanford, CA, USA.
Eric C WaitHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA.
John M HeddlestonHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA.ORCID http://orcid.org/0000-0002-9289-4114
Jeffrey J NirschlDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-6857-341X
Christopher J ObaraHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA.
Pedro Guedes-DiasDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0003-0992-5141
C Alexander BoeckerDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-9701-5273
Teng-Leong ChewHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA.ORCID http://orcid.org/0000-0002-3139-7560
Julie A TheriotDepartment of Biology, University of Washington, Seattle, WA, USA.ORCID http://orcid.org/0000-0002-2334-2535
Jennifer Lippincott-SchwartzHoward Hughes Medical Institute, Janelia Research Campus, Ashburn, VA, USA.ORCID http://orcid.org/0000-0002-8601-3501
Erika L F HolzbaurDepartment of Physiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA. holzbaur@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0001-5389-4114
Howard Hughes Medical Institute · USUniversity of Pennsylvania · USStanford University · USTechnical University of Munich · DE
Funding
Study Design and Data AnalysisP30AR069589 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI Elizabeth Anne Grice · 2016 to 2026
$8.6MIntegrative mechanisms of organelle dynamics from the atomic-to-cellular levelRM1GM136511 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DOMINGUEZ, ROBERTO, HOLZBAUR, ERIKA L · 2020 to 2024
$7.4MMolecular Mechanisms of Axonal Transport and Organelle DynamicsR35GM126950 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI Erika L Holzbaur · 2018 to 2026
$5.6MActin-Based Motility of a Bacterial PathogenR37AI036929 · NIAID · UNIVERSITY OF WASHINGTON · PI THERIOT, JULIE A. · 2010 to 2019
$3.0MRole of autophagy in epidermal differentiation and homeostasisK08AR075846 · NIAMS · UNIVERSITY OF WASHINGTON · PI SIMPSON, CORY L · 2019 to 2023
$848kPathogenic Mechanisms of Reduced Transport Initiation in Perry SyndromeF30NS092227 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI NIRSCHL, JEFFREY JOHN · 2015 to 2017
$118kRegulation of mitochondrial dynamics and homeostasis by cyclic actin assembly/disassemblyF31GM123644 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI MOORE, ANDREW S · 2017 to 2017
$43kNIAID NIH HHS R37 AI036929NIAMS NIH HHS K08 AR075846NIAMS NIH HHS P30 AR069589NIGMS NIH HHS F31 GM123644NIGMS NIH HHS R35 GM126950NIGMS NIH HHS RM1 GM136511NINDS NIH HHS F30 NS092227
Abstract
Symmetric cell division requires the even partitioning of genetic information and cytoplasmic contents between daughter cells. Whereas the mechanisms coordinating the segregation of the genome are well known, the processes that ensure organelle segregation between daughter cells remain less well understood
Indexed as
MitosisActin CytoskeletonActinsAnimalsCell DivisionCell LineCytokinesisEndoplasmic ReticulumHippocampusHumansMitochondriaNeuronsRatsActins
Identifiers
What OpenQuestion holds
Textmetadata
LicenceTDM
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.