Evidence map›Paper›PMID 33658595›Full record

ArticleScientific reports2021

Quantitative evaluation of SARS-CoV-2 inactivation using a deep ultraviolet light-emitting diode.

Takeo Minamikawa, Takaaki Koma, Akihiro Suzuki, Takahiko Mizuno, Kentaro Nagamatsu, Hideki Arimochi, Koichiro Tsuchiya, Kaoru Matsuoka, Takeshi Yasui, Koji Yasutomo and 1 more

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 88 citations in OpenAlex.

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  20. UV and violet light can Neutralize SARS-CoV-2 Infectivity.Journal of photochemistry and photobiology · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Takeo Minamikawa *Department of Post-LED Photonics Research, Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, Tokushima, 770-8506, Japan. minamikawa.takeo@tokushima-u.ac.jp.
Takaaki Koma *Department of Microbiology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, Tokushima, 770-8503, Japan.
Akihiro SuzukiDepartment of Post-LED Photonics Research, Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, Tokushima, 770-8506, Japan.
Takahiko MizunoDepartment of Post-LED Photonics Research, Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, Tokushima, 770-8506, Japan.
Kentaro NagamatsuDepartment of Post-LED Photonics Research, Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, Tokushima, 770-8506, Japan.
Hideki ArimochiDepartment of Immunology and Parasitology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, Tokushima, 770-8503, Japan.
Koichiro TsuchiyaDepartment of Medical Pharmacology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, Tokushima, 770-8503, Japan.
Kaoru MatsuokaDepartment of Post-LED Photonics Research, Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, Tokushima, 770-8506, Japan.
Takeshi YasuiDepartment of Post-LED Photonics Research, Institute of Post-LED Photonics, Tokushima University, 2-1 Minami-Josanjima, Tokushima, Tokushima, 770-8506, Japan.
Koji YasutomoDepartment of Immunology and Parasitology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, Tokushima, 770-8503, Japan.
Masako NomaguchiDepartment of Microbiology, Graduate School of Biomedical Sciences, Tokushima University, 3-18-15 Kuramoto, Tokushima, Tokushima, 770-8503, Japan. nomaguchi@tokushima-u.ac.jp.
Tokushima University · JP

Funding

The Research Clusters program of Tokushima University, Japan 1802003The Research Clusters program of Tokushima University, Japan 2001005
6 · The paper itself

Abstract

Inactivation technology for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is certainly a critical measure to mitigate the spread of coronavirus disease 2019 (COVID-19). A deep ultraviolet light-emitting diode (DUV-LED) would be a promising candidate to inactivate SARS-CoV-2, based on the well-known antiviral effects of DUV on microorganisms and viruses. However, due to variations in the inactivation effects across different viruses, quantitative evaluations of the inactivation profile of SARS-CoV-2 by DUV-LED irradiation need to be performed. In the present study, we quantify the irradiation dose of DUV-LED necessary to inactivate SARS-CoV-2. For this purpose, we determined the culture media suitable for the irradiation of SARS-CoV-2 and optimized the irradiation apparatus using commercially available DUV-LEDs that operate at a center wavelength of 265, 280, or 300 nm. Under these conditions, we successfully analyzed the relationship between SARS-CoV-2 infectivity and the irradiation dose of the DUV-LEDs at each wavelength without irrelevant biological effects. In conclusion, total doses of 1.8 mJ/cm

Indexed as

COVID-19HumansSARS-CoV-2Ultraviolet RaysUltraviolet TherapyVirus DiseasesVirus Inactivation

Identifiers

PMID33658595
PMCPMC7930116
OpenAlexW3134594595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.