Evidence map›Paper›PMID 33658553›Full record

ArticleScientific reports2021

Initiating an epilepsy surgery program with limited resources in Indonesia.

Muhamad Thohar Arifin, Ryosuke Hanaya, Yuriz Bakhtiar, Aris Catur Bintoro, Koji Iida, Kaoru Kurisu, Kazunori Arita, Jacob Bunyamin, Rofat Askoro, Surya Pratama Brilliantika and 2 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Article
  3. Epilepsy in low- to middle-income countries.Current opinion in neurology · 2025
    Review
  4. Article
  5. Epilepsy in Asian countries.Acta epileptologica · 2023
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Muhamad Thohar ArifinDepartment of Neurosurgery, Faculty of Medicine, Diponegoro University, Semarang City, Central Java Province, Indonesia. thohar@fk.undip.ac.id.
Ryosuke HanayaDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima City, Kagoshima Prefecture, Japan.
Yuriz BakhtiarDepartment of Neurosurgery, Faculty of Medicine, Diponegoro University, Semarang City, Central Java Province, Indonesia.
Aris Catur BintoroDepartment of Neurology, Faculty of Medicine, Diponegoro University, Semarang City, Central Java Province, Indonesia.
Koji IidaDepartment of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Higashihiroshima City, Hiroshima Prefecture, Japan.
Kaoru KurisuDepartment of Neurosurgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Higashihiroshima City, Hiroshima Prefecture, Japan.
Kazunori AritaDepartment of Neurosurgery, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima City, Kagoshima Prefecture, Japan.
Jacob BunyaminDepartment of Neurosurgery, Faculty of Medicine, Diponegoro University, Semarang City, Central Java Province, Indonesia.
Rofat AskoroDepartment of Neurosurgery, Faculty of Medicine, Diponegoro University, Semarang City, Central Java Province, Indonesia.
Surya Pratama BrilliantikaDepartment of Neurosurgery, Faculty of Medicine, Diponegoro University, Semarang City, Central Java Province, Indonesia.
Novita Ikbar KhairunnisaDepartment of Neurosurgery, Faculty of Medicine, Diponegoro University, Semarang City, Central Java Province, Indonesia.
Zainal MuttaqinDepartment of Neurosurgery, Faculty of Medicine, Diponegoro University, Semarang City, Central Java Province, Indonesia.
Diponegoro University · IDHiroshima University · JPKagoshima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To share the experiences of organizing the epilepsy surgery program in Indonesia. This study was divided into two periods based on the presurgical evaluation method: the first period (1999-2004), when interictal electroencephalogram (EEG) and magnetic resonance imaging (MRI) were used mainly for confirmation, and the second period (2005-2017), when long-term non-invasive and invasive video-EEG was involved in the evaluation. Long-term outcomes were recorded up to December 2019 based on the Engel scale. All 65 surgical recruits in the first period possessed temporal lobe epilepsy (TLE), while 524 patients were treated in the second period. In the first period, 76.8%, 16.1%, and 7.1% of patients with TLE achieved Classes I, II, and III, respectively, and in the second period, 89.4%, 5.5%, and 4.9% achieved Classes I, II, and III, respectively, alongside Class IV, at 0.3%. The overall median survival times for patients with focal impaired awareness seizures (FIAS), focal to bilateral tonic-clonic seizures and generalized tonic-clonic seizures were 9, 11 and 11 years (95% CI: 8.170-9.830, 10.170-11.830, and 7.265-14.735), respectively, with p = 0.04. The utilization of stringent and selective criteria to reserve surgeries is important for a successful epilepsy program with limited resources.

Indexed as

AdultAnterior Temporal LobectomyDeveloping CountriesElectroencephalographyEpilepsy, Temporal LobeEpilepsy, Tonic-ClonicFemaleFollow-Up StudiesFunctional LateralityHumansIndonesiaMagnetic Resonance ImagingMaleSeizuresSurvival RateTreatment Outcome

Identifiers

PMID33658553
PMCPMC7930083
OpenAlexW3133797666

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.