Evidence map›Paper›PMID 33658436›Full record

ArticleMolecules and cells2021

Increased Hepatic Lipogenesis Elevates Liver Cholesterol Content.

Jean-Mathieu Berger, Young-Ah Moon

Open access · diamondAbstract read
In one paragraph

Article in Molecules and cells, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.

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  13. Frontiers in cardiovascular medicine · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Jean-Mathieu BergerDepartments of Internal Medicine and Molecular Genetics, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.ORCID https://orcid.org/0000-0002-2772-4469
Young-Ah MoonDepartment of Molecular Medicine, Inha University College of Medicine, Incheon 22212, Korea.ORCID https://orcid.org/0000-0002-4569-5817
Inha University · KRThe University of Texas Southwestern Medical Center · US

Funding

TRANSCRIPTIONAL REGULATION OF LDL RECEPTOR PROMOTERP01HL020948 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI GOLDSTEIN, JOSEPH L · 1985 to 2021
$103.1M
NHLBI NIH HHS P01 HL020948
6 · The paper itself

Abstract

Cardiovascular diseases (CVDs) are the most common cause of death in patients with nonalcoholic fatty liver disease (NAFLD) and dyslipidemia is considered at least partially responsible for the increased CVD risk in NAFLD patients. The aim of the present study is to understand how hepatic

Indexed as

LipogenesisAnimalsCells, CulturedCholesterolCholesterol EstersDietDietary SucroseFatty AcidsFatty LiverFeeding BehaviorHepatocytesHypercholesterolemiaLipid DropletsLipoproteinsLiverMaleCholesterolCholesterol EstersDietary SucroseFatty AcidsLipoproteinsReceptors, LDLTriglyceridescholesteroldyslipidemiafatty liverlipogenesis

Identifiers

PMID33658436
PMCPMC7941001
OpenAlexW3134374537

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.