Evidence map›Paper›PMID 33658396›Full record

ArticleAging2021

Prognostic significance of epigenetic regulatory gene expression in patients with non-small-cell lung cancer.

Zegui Tu, Xiancheng Chen, Tian Tian, Guo Chen, Meijuan Huang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Zegui TuDepartment of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, P.R. China.
Xiancheng ChenState Key Laboratory of Biotherapy/Collaborative Innovation Center for Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, P.R. China.
Tian TianDepartment of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, P.R. China.
Guo ChenGlobal Infotech Software Limited Corporation, Chengdu 610041, Sichuan, P.R. China.
Meijuan HuangDepartment of Thoracic Oncology, West China Hospital of Sichuan University, Chengdu 610041, Sichuan, P.R. China.
Sichuan University · CNWest China Hospital of Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In this study, we used public databases to investigate the prognostic significance of epigenetic regulatory gene expression in patients with non small-cell lung cancer (NSCLC). Oncomine database analysis showed that the mRNA levels of seven epigenetic regulatory genes,

Indexed as

Adenosine TriphosphatasesCarcinoma, Non-Small-Cell LungCCAAT-Enhancer-Binding ProteinsDNA-Binding ProteinsDNA HelicasesDNA RepairEnhancer of Zeste Homolog 2 ProteinEpigenesis, GeneticGene Expression Regulation, NeoplasticGenetic Predisposition to DiseaseHistone-Lysine N-MethyltransferaseHumansKaplan-Meier EstimateLung NeoplasmsPrognosisProliferating Cell Nuclear AntigenAdenosine TriphosphatasesCCAAT-Enhancer-Binding ProteinsDNA-Binding ProteinsDNA HelicasesEnhancer of Zeste Homolog 2 ProteinEZH2 protein, humanHistone-Lysine N-MethyltransferaseNSD2 protein, humanPCNA protein, humanProliferating Cell Nuclear AntigenRAD54L protein, humanRepressor ProteinsSUV39H2 protein, humanTranscription FactorsTTF2 protein, humanUbiquitin-Protein LigasesUHRF1 protein, humanepigenetic regulatory genesexpression patternsnon-small-cell lung cancerprognosis

Identifiers

PMID33658396
PMCPMC7993691
OpenAlexW3135674572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.