Evidence map›Paper›PMID 33658263›Full record

ArticleJournal of clinical microbiology2021

Reflex Detection of Ciprofloxacin Resistance in Neisseria gonorrhoeae by Use of the SpeeDx ResistancePlus GC Assay.

Darren Y J Lee, Melinda M Ashcroft, Eric P F Chow, Michelle Sait, Vesna De Petra, Marlene Tschaepe, Sigrid Lange, George Taiaroa, Catriona S Bradshaw, David M Whiley and 5 more

Abstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Current and Emerging Approaches and Technologies for Rapid Detection of Neisseria gonorrhoeae Antimicrobial Resistance.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Review
  3. Evaluation of the Allplex NG & DR assay for molecular prediction of ciprofloxacin and azithromycin resistance in Neisseria gonorrhoeae.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  4. Review
  5. Article
  6. Article
  7. Rapid molecular phenotypic antimicrobial susceptibility test forbioRxiv : the preprint server for biology · 2023
    Article
  8. Review
  9. Management of Pelvic Inflammatory Disease in Clinical Practice.Therapeutics and clinical risk management · 2023
    Review
  10. The Optimal Management ofMicroorganisms · 2022
    Review
  11. Tolerance to Ceftriaxone inAntibiotics (Basel, Switzerland) · 2022
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Darren Y J LeeDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-6742-2310
Melinda M AshcroftDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-9157-4533
Eric P F ChowMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.ORCID 0000-0003-1766-0657
Michelle SaitMicrobiological Diagnostic Unit Public Health Laboratory, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Vesna De PetraMicrobiological Diagnostic Unit Public Health Laboratory, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Marlene TschaepeMicrobiological Diagnostic Unit Public Health Laboratory, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Sigrid LangeMicrobiological Diagnostic Unit Public Health Laboratory, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
George TaiaroaDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Catriona S BradshawMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.
David M WhileyThe University of Queensland Centre for Clinical Research (UQ-CCR), Faculty of Medicine, The University of Queensland, Brisbane, Queensland, Australia.
Christopher K FairleyMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.
Benjamin P HowdenMicrobiological Diagnostic Unit Public Health Laboratory, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.
Marcus Y ChenMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.
Shivani PasrichaDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia.ORCID 0000-0001-9681-1956
Deborah A WilliamsonDepartment of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, Victoria, Australia deborah.williamson@unimelb.edu.au.ORCID 0000-0001-7363-6665

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resistance-guided therapy (RGT) for gonorrhea may reduce unnecessary use of broad-spectrum antibiotics. When reflexed from the Aptima Combo 2 assay, the ResistancePlus GC assay demonstrated 94.8% sensitivity and 100.0% specificity for

Indexed as

GonorrheaNeisseria gonorrhoeaeAnti-Bacterial AgentsCiprofloxacinDrug Resistance, BacterialHumansMicrobial Sensitivity TestsReflexAnti-Bacterial AgentsCiprofloxacinantimicrobial resistancemolecular diagnosticNeisseria gonorrhoeaewhole-genome sequencing

Identifiers

PMID33658263
PMCPMC8091848

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.