SynthesisJournal of medical Internet research2021
Voice-Based Conversational Agents for the Prevention and Management of Chronic and Mental Health Conditions: Systematic Literature Review.
Synthesis in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
44 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Chatbot interventions for improving mental health among people in Asia: a systematic review and meta-analysis of randomised controlled trials.BMJ health & care informatics · 2026Pooled it
- Conversational Agents Supporting Self-Management in People With a Chronic Disease: Systematic Review.Journal of medical Internet research · 2025Pooled it
- Effectiveness and acceptability of conversational agents for sexual health promotion: a systematic review and meta-analysis.Sexual health · 2022Pooled it
- Evaluating Older Adults' Engagement and Usability With AI-Driven Interventions: Randomized Pilot Study.JMIR formative research · 2025Trial
- Cognitive Reablement Using Digital Voice Assistants for People Living With Dementia or Mild Cognitive Impairment: A Co-Design Study.Health expectations : an international journal of public participation in health care and health policy · 2026Article
- Voice-assisted artificial intelligence in cardiovascular disease management: a systematic review and meta-analysis protocol.BMJ open · 2026Article
- Managing maternity: Moving care, not patients, using artificial intelligence (AI), internet-of-things (IOT) and point-of-care testing (POCT) devices.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Article
- Potential Use of Voice-Activated Personal Assistants in Diabetes Prevention and Management: An Exploratory Qualitative Study Using the Consolidated Framework for Implementation Research.Health promotion practice · 2026Article
- Mental health chatbots and their technical features: A systematic review of reviews and a thematic analysis.Global mental health (Cambridge, England) · 2026Review
- Application of emerging information technologies in the prevention and control of chronic diseases.Frontiers in public health · 2026Review
- Article
- Bridging the rural oncology gap: A conceptual, technical, and pragmatic framework for digital interventions.Cancer · 2025Article
- Refining smart healthcare care for mental health and substance use disorders: A patient-centred, evidence-based approach.World journal of psychiatry · 2025Article
- User Engagement with A Multimodal Conversational Agent for Self-Care and Chronic Disease Management: A Retrospective Analysis.Journal of medical systems · 2025Article
- Modernizing the Staging of Parkinson Disease Using Digital Health Technology.Journal of medical Internet research · 2025Article
- Health Care Professionals' Engagement With Digital Mental Health Interventions in the United Kingdom and China: Mixed Methods Study on Engagement Factors and Design Implications.JMIR mental health · 2025Article
- Precision management in chronic disease: An AI empowered perspective on medicine-engineering crossover.iScience · 2025Review
- Leveraging voice biomarkers to quantify chronic pain: a rapid review.Frontiers in pain research (Lausanne, Switzerland) · 2025Review
- Effectiveness of chatbot-based interventions on mental well-being of the general population in Asia: protocol for a systematic review and meta-analysis of randomised controlled trials.BMJ health & care informatics · 2024Article
- Roles, Users, Benefits, and Limitations of Chatbots in Health Care: Rapid Review.Journal of medical Internet research · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic and mental health conditions are increasingly prevalent worldwide. As devices in our everyday lives offer more and more voice-based self-service, voice-based conversational agents (VCAs) have the potential to support the prevention and management of these conditions in a scalable manner. However, evidence on VCAs dedicated to the prevention and management of chronic and mental health conditions is unclear.
objectiveThis study provides a better understanding of the current methods used in the evaluation of health interventions for the prevention and management of chronic and mental health conditions delivered through VCAs.
methodsWe conducted a systematic literature review using PubMed MEDLINE, Embase, PsycINFO, Scopus, and Web of Science databases. We included primary research involving the prevention or management of chronic or mental health conditions through a VCA and reporting an empirical evaluation of the system either in terms of system accuracy, technology acceptance, or both. A total of 2 independent reviewers conducted the screening and data extraction, and agreement between them was measured using Cohen kappa. A narrative approach was used to synthesize the selected records.
resultsOf 7170 prescreened papers, 12 met the inclusion criteria. All studies were nonexperimental. The VCAs provided behavioral support (n=5), health monitoring services (n=3), or both (n=4). The interventions were delivered via smartphones (n=5), tablets (n=2), or smart speakers (n=3). In 2 cases, no device was specified. A total of 3 VCAs targeted cancer, whereas 2 VCAs targeted diabetes and heart failure. The other VCAs targeted hearing impairment, asthma, Parkinson disease, dementia, autism, intellectual disability, and depression. The majority of the studies (n=7) assessed technology acceptance, but only few studies (n=3) used validated instruments. Half of the studies (n=6) reported either performance measures on speech recognition or on the ability of VCAs to respond to health-related queries. Only a minority of the studies (n=2) reported behavioral measures or a measure of attitudes toward intervention-targeted health behavior. Moreover, only a minority of studies (n=4) reported controlling for participants' previous experience with technology. Finally, risk bias varied markedly.
conclusionsThe heterogeneity in the methods, the limited number of studies identified, and the high risk of bias show that research on VCAs for chronic and mental health conditions is still in its infancy. Although the results of system accuracy and technology acceptance are encouraging, there is still a need to establish more conclusive evidence on the efficacy of VCAs for the prevention and management of chronic and mental health conditions, both in absolute terms and in comparison with standard health care.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.