Evidence map›Paper›PMID 33657997›Full record

ArticleBMC pediatrics2021

Kaposiform haemangioendothelioma: magnetic resonance imaging features in 64 cases.

Suhua Peng, Chunchao Xia, Kaiying Yang, Siyuan Chen, Yi Ji

Open access · goldAbstract read
In one paragraph

Article in BMC pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Primary osseous kaposiform hemangioendothelioma confined to long bones: a retrospective imaging analysis of 12 pediatric cases.Cancer imaging : the official publication of the International Cancer Imaging Society · 2026
    Article
  6. Article
  7. Article
  8. Review
  9. Analysis of ultrasound and magnetic resonance imaging characteristics of kaposiform hemangioen dothelioma.Cancer imaging : the official publication of the International Cancer Imaging Society · 2024
    Article
  10. Imaging of Vascular Anomalies.Seminars in interventional radiology · 2024
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Suhua Peng *Division of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, #37 Guo-Xue-Xiang, 610041, Chengdu, China.
Chunchao Xia *Department of Radiology, West China Hospital of Sichuan University, 610041, Chengdu, China.
Kaiying YangDivision of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, #37 Guo-Xue-Xiang, 610041, Chengdu, China.
Siyuan ChenPediatric Intensive Care Unit, Department of Critical Care Medicine, West China Hospital of Sichuan University, #37 Guo-Xue-Xiang, 610041, Chengdu, China. siy_chen@163.com.
Yi JiDivision of Oncology, Department of Pediatric Surgery, West China Hospital of Sichuan University, #37 Guo-Xue-Xiang, 610041, Chengdu, China. jijiyuanyuan@163.com.ORCID 0000-0002-9289-9660
Sichuan University · CN

Funding

1.3.5 project for disciplines of excellence, West China Hospital, Sichuan University 2019HXFH0561.3.5 project for disciplines of excellence, West China Hospital, Sichuan University 2020HXFH048Key Project in the Science & Technology Program of Sichuan Province 2019YFS0322National Natural Science Foundation of China 81400862National Natural Science Foundation of China 81401606Science Foundation for Excellent Youth Scholars of Sichuan University 2015SU04A15
6 · The paper itself

Abstract

backgroundKaposiform haemangioendothelioma (KHE) is a rare, locally aggressive disorder. The presenting and imaging features of KHE can overlap with other vascular anomalies and tumours. We aimed to analyse the imaging findings of KHE disorder and highlight features most suggestive of this diagnosis.

methodsThe clinical features and imaging findings were retrospectively reviewed in 64 patients with pathological diagnosis of KHE.

resultsOf the 64 patients diagnosed with KHE, 36 patients were < 6 months and 28 patients were ≥ 6 months. The most common presenting features were Kasabach-Merritt phenomenon (KMP, 42.2 %), visible cutaneous lesions (90.6 %), oedema or swelling (43.8 %) and destructive changes or remodelling of adjacent bone (42.2 %). Compared with patients in the group ≥ 6 months, patients in the group < 6 months have higher odds of KMP (P = 0.000), infiltrative lesion with ill-defined borders (P = 0.044). The group ≥ 6 months have higher odds of destructive changes or remodelling of adjacent bone (P = 0.002). In all patients, the lesions in all of the 64 patients were hypointense or isointense compared with muscle on T1-weighted sequences, and hyperintense on T2-weighted or inversion-recovery sequences, nine patients (14.1 %) showed vascularity. There were 28 patients (43.8 %) with characteristic enhancing and infiltrative soft-tissue thickening.

conclusionsPresence of visible cutaneous lesions with ill-defined borders, destructive changes or remodelling of adjacent bone, severe thrombocytopenia and consumptive coagulopathy should favour the diagnosis of KHE.

Indexed as

HemangioendotheliomaKasabach-Merritt SyndromeHumansMagnetic Resonance ImagingRetrospective StudiesSarcoma, KaposiKaposiform haemangioendotheliomaKasabach-merritt phenomenonMagnetic resonance imagingRadiography

Identifiers

PMID33657997
PMCPMC7927413
OpenAlexW3134022626

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.