Evidence map›Paper›PMID 33657879›Full record

ArticleArteriosclerosis, thrombosis, and vascular biology2021

Circular RNA Calm4 Regulates Hypoxia-Induced Pulmonary Arterial Smooth Muscle Cells Pyroptosis via the Circ-Calm4/miR-124-3p/PDCD6 Axis.

Yuan Jiang, Huiyu Liu, Hang Yu, Yang Zhou, Junting Zhang, Wei Xin, Yiying Li, Siyu He, Cui Ma, Xiaodong Zheng and 5 more

Abstract read
In one paragraph

Article in Arteriosclerosis, thrombosis, and vascular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
55citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

55 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Are RNA Therapies a Solid Foundation or a Frontier Yet to Be Conquered?International journal of molecular sciences · 2026
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yuan Jiang *Central Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Huiyu Liu *Central Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Hang YuCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Yang ZhouDepartment of Medical Oncology, The Third Affiliated Hospital of Harbin Medical University, China (Y.Z.).
Junting ZhangCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Wei XinCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Yiying LiCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Siyu HeCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Cui MaCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Xiaodong ZhengCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Lixin ZhangDepartment of Pharmacology, the State-Province Key Laboratories of Biomedicine-Pharmaceutics of China, Key Laboratory of Cardiovascular Research, Ministry of Education, College of Pharmacy, Harbin Medical University, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.Z., X. Zhao, D.Z.).
Xijuan ZhaoCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).
Bingxiang Wu
Chun JiangDepartment of Biology, Georgia State University, Atlanta, GA (C.J.).
Daling ZhuCentral Laboratory of Harbin Medical University, Daqing, China (Y.J., H.L., H.Y., J.Z., W.X., Y.L., S.H., C.M., X. Zheng, L.X., X. Zhao, D.Z.).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

[Figure: see text].

Indexed as

PyroptosisAnimalsApoptosis Regulatory ProteinsCalcium-Binding ProteinsCells, CulturedDisease Models, AnimalHypertension, PulmonaryMaleMiceMice, Inbred C57BLMicroRNAsMuscle, Smooth, VascularMyocytes, Smooth MusclePulmonary ArteryRNA, CircularSignal TransductionApoptosis Regulatory ProteinsCalcium-Binding ProteinsMicroRNAsMirn124 microRNA, mousePdcd6 protein, mouseRNA, Circularfluorescencehypertension, pulmonaryphenotypepyroptosisupregulation

Identifiers

PMID33657879
PMCPMC8057524

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.