Evidence map›Paper›PMID 33657872›Full record

ArticleGlobal spine journal2023

Evaluating Screw Stability After Pedicle Screw Fixation With PEEK Rods.

Jie Wu, Lei Shi, Daohong Liu, Zhigang Wu, Peng Gao, Wenwen Liu, Xiaokang Li, Zheng Guo

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jie Wu540274Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China.ORCID 0000-0002-6572-9762
Lei Shi540274Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China.
Daohong LiuDepartment of Orthopaedics, 12509the 8th Medical Center of Chinese PLA General Hospital, Beijing, China.
Zhigang Wu540274Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China.
Peng Gao540274Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China.
Wenwen Liu540274Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China.
Xiaokang Li540274Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China.
Zheng Guo540274Department of Orthopedics, Xijing Hospital, Fourth Military Medical University, Xi'an, Shanxi, China.
Xijing Hospital · CNChinese PLA General Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designAnimal experiment.

objectiveTo evaluate whether the use of polyetheretherketone (PEEK) rods for posterior spinal fixation can improve screw stability.

methodsSheep models of anterior-posterior cervical fusion were used in this study. Six sheep were randomly assigned to the PEEK rod group and titanium alloy group. A total of 8 screws and 2 fixing rods were implanted in each sheep. At 24 weeks postoperatively, a computed tomography (CT) evaluation, pull-out test, micro-CT evaluation and histological evaluation were conducted to evaluate screw stability in the harvested surgical segments.

resultAccording to the CT evaluation, there were no signs of screw loosening in either group. The pull-out force and energy of the PEEK rod group were significantly higher than those of the titanium alloy rod group. Denser and thicker trabecular bone around the screw was observed in the PEEK rod group according to the micro-CT reconstructed images, and quantitative analysis of the micro-CT data confirmed this finding. In the histological evaluation, more abundant and denser bone trabeculae were also observed in the PEEK rod group. However, there was no significant difference in the bone-screw interface between the 2 groups.

conclusionPosterior spinal fixation with PEEK rods can increase screw stability by promoting bone growth around the screw but cannot promote bone integration at the bone-screw interface in an animal model study. This finding presents a new idea for clinical practices to reduce screw loosening rate.

Indexed as

cervical vertebrapedicle screwPEEK rodscrew loosening

Identifiers

PMID33657872
PMCPMC9972285
OpenAlexW3135031621

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.