ArticlePLoS neglected tropical diseases2021
Household rat infestation in urban slum populations: Development and validation of a predictive score for leptospirosis.
Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 31 citations in OpenAlex.
- Pharmaceutical Pollutants in Urban Rats Are Linked to Zoonotic Infection Risk.Environmental science & technology letters · 2026Article
- Zoonotic transmission risk in flood-prone river basins: community knowledge and behavioral determinants of leptospirosis in eastern Ethiopia.BMC public health · 2026Article
- Leptospirosis in Southeast Asia: Investigating Seroprevalence, Transmission Patterns, and Diagnostic Challenges.Tropical medicine and infectious disease · 2026Review
- Occupation as an associated risk factor for leptospirosis.Frontiers in public health · 2026Article
- Leptospirosis seroprevalence and exposure factors in three informal settlements of French Guiana: An opportunistic survey.PLoS neglected tropical diseases · 2025Article
- In-house isolation protocol from human serum samples demonstrates the circulating of a broad diversity of Leptospira serogroups in Costa Rica.Scientific reports · 2025Article
- Systematic surveillance tools to reduce rodent pests in disadvantaged urban areas can empower communities and improve public health.Scientific reports · 2024Article
- Spatial Owner-Dog Seroprevalence ofTropical medicine and infectious disease · 2023Article
- Zoonotic febrile illnesses misdiagnosed as COVID-19: a review of reported clinical cases.Le infezioni in medicina · 2023Review
- Seroprevalence, distribution, and risk factors for human leptospirosis in the United States Virgin Islands.PLoS neglected tropical diseases · 2022Article
- Article
- Population dynamics of synanthropic rodents after a chemical and infrastructural intervention in an urban low-income community.Scientific reports · 2022Article
- Host and Species-Specificities of Pattern Recognition Receptors Upon Infection WithFrontiers in cellular and infection microbiology · 2022Review
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Authors and funding
11 authors at 3 institutions in 2 countries.
Funding
Abstract
Domestic rats are the principal reservoir for urban leptospirosis. However, few studies have identified infestation markers in slums and evaluated their predictivity for leptospirosis risk. We compared households with leptospirosis cases in Salvador, Brazil between 2007 and 2009 and their neighbors using a case control design, surveying for rodent infestation signs and environmental characteristics. With the 2007-2008 data, a conditional logistic regression modeling identified the peridomiciliar presence of rodent burrows (OR, 3.30; 95% CI, 1.50-7.26), rat feces (2.86; 1.24-6.59), runs (2.57; 1.06-6.22), households bordering abandoned houses (2.48; 1.04-6.02), and unplastered walls (2.22; 1.02-6.02) as risk factors and developed a predictive score for leptospirosis. With an independent data set from 2009, a receiver operating characteristic (ROC) curve analysis evaluated the prediction score performance, with the area under the curve being 0.70 (95% CI, 0.64-0.76) for score development and 0.71 (0.65-0.79) for validation. Results indicate that high proportions of urban slum households are infested with R. norvegicus. The score performed well when identifying high-risk households within slums. These findings need confirmation in other urban centers, but suggest that community-based screening for rodent infestation can allow to target rodent and environmental control measures in populations at highest risk for leptospirosis.
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