Evidence map›Paper›PMID 33656867›Full record

ArticleChemical research in toxicology2021

Integrative Analysis of lncRNA-mRNA Coexpression in Human Lung Epithelial Cells Exposed to Dimethyl Selenide-Derived Secondary Organic Aerosols.

C M Sabbir Ahmed, Biplab Chandra Paul, Yumeng Cui, Alexander L Frie, Abigail Burr, Rohan Kamath, Jin Y Chen, Tara M Nordgren, Roya Bahreini, Ying-Hsuan Lin

Abstract read
In one paragraph

Article in Chemical research in toxicology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

C M Sabbir AhmedEnvironmental Toxicology Graduate Program, University of California, Riverside, California 92521, United States.ORCID 0000-0002-7254-2955
Biplab Chandra PaulGastrointestinal Unit, Massachusetts General Hospital, Boston, Massachusetts 02114, United States.
Yumeng CuiDepartment of Environmental Sciences, University of California, Riverside, California 92521, United States.
Alexander L FrieDepartment of Environmental Sciences, University of California, Riverside, California 92521, United States.
Abigail BurrDivision of Biomedical Sciences, University of California, Riverside, California 92521, United States.
Rohan KamathDivision of Biomedical Sciences, University of California, Riverside, California 92521, United States.
Jin Y ChenEnvironmental Toxicology Graduate Program, University of California, Riverside, California 92521, United States.ORCID 0000-0002-6034-9971
Tara M NordgrenEnvironmental Toxicology Graduate Program, University of California, Riverside, California 92521, United States.
Roya BahreiniEnvironmental Toxicology Graduate Program, University of California, Riverside, California 92521, United States.ORCID 0000-0001-8292-5338
Ying-Hsuan LinEnvironmental Toxicology Graduate Program, University of California, Riverside, California 92521, United States.ORCID 0000-0001-8904-1287
University of California, Riverside · USHarvard University · US

Funding

Acquisition of a Scalable Storage Cluster for Data Intensive NIH ResearchS10OD016290 · OD · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI GIRKE, THOMAS · 2014 to 2014
$593k
NIH HHS S10 OD016290
6 · The paper itself

Abstract

Dimethyl selenide (DMSe) is one of the major volatile organoselenium compounds released into the atmosphere through plant metabolism and microbial methylation. DMSe has been recently revealed as a precursor of secondary organic aerosol (SOA), and its resultant SOA possesses strong oxidizing capability toward thiol groups that can perturb several major biological pathways in human airway epithelial cells and is linked to genotoxicity, DNA damage, and p53-mediated stress responses. Mounting evidence has suggested that long noncoding RNAs (lncRNAs) are involved in stress responses to internal and environmental stimuli. However, the underlying molecular interactions remain to be elucidated. In this study, we performed integrative analyses of lncRNA-mRNA coexpression in the transformed human bronchial epithelial BEAS-2B cell line exposed to DMSe-derived SOA. We identified a total of 971 differentially expressed lncRNAs in BEAS-2B cells exposed to SOA derived from O

Indexed as

AerosolsCells, CulturedEpithelial CellsHumansLungOrganoselenium CompoundsRNA, Long NoncodingRNA, MessengerRNA-SeqAerosolsdimethylselenideOrganoselenium CompoundsRNA, Long NoncodingRNA, Messenger

Identifiers

PMID33656867
PMCPMC13152190
OpenAlexW3134957946

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.