Evidence map›Paper›PMID 33656783›Full record

ArticleArtificial organs2021

Efficacy of multidisciplinary team approach with extracorporeal membrane oxygenation for COVID-19 in a low volume ECMO center.

Eiki Nagaoka, Hirokuni Arai, Toyomu Ugawa, Takahiro Masuda, Kanae Ochiai, Meiyo Tamaoka, Naoki Kurashima, Keiji Oi, Tatsuki Fujiwara, Masayuki Yoshida and 2 more

Abstract read
In one paragraph

Article in Artificial organs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A Novel Method for Predicting Recirculation by Sweep-Gas Control in Extracorporeal Membrane Oxygenation.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Eiki NagaokaDepartment of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.ORCID https://orcid.org/0000-0002-3768-8692
Hirokuni AraiDepartment of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Toyomu UgawaDepartment of Intensive Care Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Takahiro MasudaDepartment of Intensive Care Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Kanae OchiaiTrauma and Acute Critical Care Center, Tokyo Medical and Dental University, Tokyo, Japan.
Meiyo TamaokaDepartment of Respiratory Physiology and Sleep Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Naoki KurashimaMedical Engineering Center, Tokyo Medical and Dental University, Tokyo, Japan.
Keiji OiDepartment of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.
Tatsuki FujiwaraDepartment of Cardiovascular Surgery, Tokyo Medical and Dental University, Tokyo, Japan.ORCID https://orcid.org/0000-0002-6931-1152
Masayuki YoshidaDivision of Medical Genetics, Medical Hospital of Tokyo Medical and Dental University, Tokyo, Japan.
Hidenobu ShigemitsuDepartment of Intensive Care Medicine, Tokyo Medical and Dental University, Tokyo, Japan.
Yasuhiro OtomoTrauma and Acute Critical Care Center, Tokyo Medical and Dental University, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Veno-venous extracorporeal membrane oxygenation (VV ECMO) is an effective and proven adjunct support for various severe respiratory failures requiring invasive mechanical ventilation and cardiovascular support. In response to the rapidly increasing number of COVID-19 patients in Japan, we launched an ECMO support team comprised of multidisciplinary experts including physicians, nurses, perfusionists, and bioethicists in preparation for the threat of a pandemic. From April 2 to July 15, 2020, Tokyo Medical and Dental University hospital treated 104 PCR confirmed COVID-19 patients. Among those, 34 patients were admitted to intensive care unit (ICU) and 5 patients required VV ECMO. All management related to ECMO was decided by the ECMO support team in addition to participation of the ECMO support team in daily multidisciplinary rounds in the ICU. Median age was 54 years old. Duration from onset to mechanical ventilation (MV) and MV to ECMO were 8 and 7 days, respectively. Four patients (80%) were successfully weaned off from ECMO. One patient died after 81 days of ECMO run. Four patients were discharged and recovered to their prehospital quality of life without major disability. We achieved a high survival rate using ECMO in our low volume ECMO institution during the COVID-19 pandemic. Multidisciplinary decision-making and a team approach for the unclear pathology with an emerging infectious disease was effective and contributed to the survival rate.

Indexed as

Extracorporeal Membrane OxygenationHospitals, Low-VolumePatient Care TeamAdultAgedCooperative BehaviorCOVID-19FemaleHospital MortalityHumansInterdisciplinary CommunicationMaleMiddle AgedRecovery of FunctionRespiration, ArtificialRetrospective Studiesacute respiratory distress syndromecoronavirus disease 2019team approachveno-venous extracorporeal membrane oxygenation

Identifiers

PMID33656783
PMCPMC8014198

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.