Evidence map›Paper›PMID 33656578›Full record

ArticleBrain structure & function2021

Anodal tDCS modulates specific processing codes during conflict monitoring associated with superior and middle frontal cortices.

Nico Adelhöfer, Ann-Kathrin Stock, Christian Beste

Abstract read
In one paragraph

Article in Brain structure & function, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Nico Adelhöfer *Cognitive Neurophysiology, Faculty of Medicine, Department of Child and Adolescent Psychiatry, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Ann-Kathrin Stock *Cognitive Neurophysiology, Faculty of Medicine, Department of Child and Adolescent Psychiatry, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany.
Christian Beste *Cognitive Neurophysiology, Faculty of Medicine, Department of Child and Adolescent Psychiatry, TU Dresden, Fetscherstrasse 74, 01307, Dresden, Germany. christian.beste@uniklinikum-dresden.de.ORCID http://orcid.org/0000-0002-2989-9561

Funding

Deutsche Forschunggemeinschaft BE4045/26-1Deutsche Forschungsgemeinschaft FOR 2698
6 · The paper itself

Abstract

Conflict monitoring processes are central for cognitive control. Neurophysiological correlates of conflict monitoring (i.e. the N2 ERP) likely represent a mixture of different cognitive processes. Based on theoretical considerations, we hypothesized that effects of anodal tDCS (atDCS) in superior frontal areas affect specific subprocesses in neurophysiological activity during conflict monitoring. To investigate this, young healthy adults performed a Simon task while EEG was recorded. atDCS and sham tDCS were applied in a single-blind, cross-over study design. Using temporal signal decomposition in combination with source localization analyses, we demonstrated that atDCS effects on cognitive control are very specific: the detrimental effect of atDCS on response speed was largest in case of response conflicts. This however only showed in aspects of the decomposed N2 component, reflecting stimulus-response translation processes. In contrast to this, stimulus-related aspects of the N2 as well as purely response-related processes were not modulated by atDCS. EEG source localization analyses revealed that the effect was likely driven by activity modulations in the superior frontal areas, including the supplementary motor cortex (BA6), as well as middle frontal (BA9) and medial frontal areas (BA32). atDCS did not modulate effects of proprioceptive information on hand position, even though this aspect is known to be processed within the same brain areas. Physiological effects of atDCS likely modulate specific aspects of information processing during cognitive control.

Indexed as

Motor CortexTranscranial Direct Current StimulationCross-Over StudiesHandHumansSingle-Blind MethodAnodal tDCSConflict monitoringEEGSuperior frontal cortex

Identifiers

PMID33656578
PMCPMC8036188

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.