Evidence map›Paper›PMID 33656251›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2021

Cognitive measures lacking in EHR prior to dementia or Alzheimer's disease diagnosis.

Nancy Maserejian, Henry Krzywy, Susan Eaton, James E Galvin

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Distinct medical and substance use histories associate with cognitive decline in Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Detection and Diagnosis of Early Symptomatic Alzheimer's Disease in Primary Care.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2024
    Article
  11. Article
  12. Observational
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Cognitive measures lacking in EHR prior to dementia or Alzheimer's disease diagnosis.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nancy MaserejianBiogen, Cambridge, Massachusetts, USA.
Henry KrzywyBiogen, Cambridge, Massachusetts, USA.
Susan EatonBiogen, Cambridge, Massachusetts, USA.
James E GalvinDepartment of Neurology, Comprehensive Center for Brain Health, University of Miami Miller School of Medicine, Miami, Florida, USA.

Funding

Multicultural Community Dementia ScreeningR01AG071514 · NIA · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALVIN, JAMES E · 2021 to 2025
$13.8M
Reducing Disparities in Dementia and VCID Outcomes in a Multicultural Rural PopulationR01NS101483 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI GALVIN, JAMES E · 2019 to 2023
$8.0M
Digital Detection of Dementia Studies (D cubed Studies).R01AG069765 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI BEN-MILED, ZINA, BOUSTANI, MALAZ · 2020 to 2024
$4.9M
Multicultural Community Dementia Screening.R01AG040211 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI GALVIN, JAMES E · 2011 to 2018
$3.2M
NIA NIH HHS R01 AG040211NIA NIH HHS R01 AG071514NINDS NIH HHS R01 NS101483
6 · The paper itself

Abstract

introductionThe extent that cognitive measures are documented in electronic health records (EHR) is important for quality care and addressing disparities in timely diagnosis of dementia or Alzheimer's disease (AD).

methodsAnalysis of U.S. EHR data to describe the frequency and factors associated with cognitive measures prior to diagnosis of dementia (N = 111,125) or AD (N = 30,203).

resultsOnly 11% of dementia patients and 24% of AD patients had a cognitive measure documented in the 5 years prior to diagnosis. Black race, older age, non-commercial health insurance, lower mean neighborhood income, greater in-patient stays, and fewer out-patient visits were associated with lacking cognitive measures. DISCUSSION: Extensive missing cognitive data and differences in the availability of cognitive measures by race, age, and socioeconomic factors hinder patient care and limit utility of EHR for dementia research. Structured fields and prompts for cognitive data inputs at the point of care may help address these gaps.

Indexed as

AgedAged, 80 and overAlzheimer DiseaseElectronic Health RecordsFemaleHumansMaleMental Status and Dementia TestsAlzheimer's diseasedementiaelectronic health recordselectronic medical recordshealthcare disparitiesmild cognitive impairmentMini-Mental State Examinationneurocognitive tests

Identifiers

PMID33656251
PMCPMC8359414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.