Evidence map›Paper›PMID 33656168›Full record

ArticleBiotechnology and bioengineering2021

Media on-demand: Continuous reconstitution of a chemically defined media directly from solids.

Daniel Komuczki, Gregory Dutra, Christoph Gstöttner, Elena Dominguez-Vega, Alois Jungbauer, Peter Satzer

Open access · hybridAbstract read
In one paragraph

Article in Biotechnology and bioengineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Daniel KomuczkiDepartment of Biotechnology, Institute of Bioprocess Science and Engineering, University of Natural Resources and Life Sciences, Vienna, Austria.ORCID 0000-0001-9246-773X
Gregory DutraDepartment of Biotechnology, Institute of Bioprocess Science and Engineering, University of Natural Resources and Life Sciences, Vienna, Austria.
Christoph GstöttnerCenter for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.ORCID 0000-0003-4033-4024
Elena Dominguez-VegaCenter for Proteomics and Metabolomics, Leiden University Medical Center, Leiden, Netherlands.ORCID 0000-0002-6394-0783
Alois JungbauerDepartment of Biotechnology, Institute of Bioprocess Science and Engineering, University of Natural Resources and Life Sciences, Vienna, Austria.ORCID 0000-0001-8182-7728
Peter SatzerDepartment of Biotechnology, Institute of Bioprocess Science and Engineering, University of Natural Resources and Life Sciences, Vienna, Austria.ORCID 0000-0003-3907-4755
Austrian Centre of Industrial Biotechnology (Austria) · ATBOKU University · ATLeiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemically defined media are reconstituted batchwise and stored in hold tanks until use. To avoid large hold tanks and batchwise production of media, we developed continuous on-demand reconstitutions directly from solids consisting of a hopper and a screw conveyor capable of feeding dry powdered media with the required precision ±5% at low dosing rates of 0.171 g min

Indexed as

BioreactorsAnimalsAntibodies, MonoclonalCHO CellsCricetulusCulture MediaAntibodies, MonoclonalCulture MediaCDMCHOcontinuousIgGsolid

Identifiers

PMID33656168
PMCPMC8451748
OpenAlexW3134517900

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.