SynthesisBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2021
Obesity as a predictive factor for chronic kidney disease in adults: systematic review and meta-analysis.
Synthesis in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
- Visceral Adiposity and Renal Health: From Pathophysiological Mechanisms to Novel Therapeutic Strategies.Journal of clinical medicine · 2026Review
- Mechanisms of Obesity-Related Kidney Disease: From Adipose Depot Biology to the Chymase-Aldosterone and Ghrelin-Leptin Axes.Biomolecules · 2026Review
- Hyperaldosteronism in the Pathophysiology and Management of Cardiovascular-Kidney-Metabolic Syndrome.Diabetes, obesity & metabolism · 2026Review
- Review
- Review
- Bariatric surgery: is an alternative for patients with obesity class III on dialysis, future kidney transplantation candidates?Updates in surgery · 2026Article
- Beyond Numbers: CKD-EPI Versus MDRD in Primary Care-Differences in Chronic Kidney Disease Stage Classification in 117,055 Patients.Journal of clinical medicine · 2026Article
- Insulin Resistance at the Crossroads of Metabolic Inflammation, Cardiovascular Disease, Organ Failure and Cancer.Biomolecules · 2025Review
- Relationships Between Metabolic and Bariatric Surgery and Adverse Kidney Outcomes: An Analysis of a Retrospective Cohort.Obesity science & practice · 2025Article
- Trends and economic inequalities in obesity prevalence in Ghana: a cross-sectional study spanning 2008-2022.Journal of health, population, and nutrition · 2025Article
- Potential Therapeutic Exploitation of G Protein-Coupled Receptor 120 (GPR120/FFAR4) Signaling in Obesity-Related Metabolic Disorders.International journal of molecular sciences · 2025Review
- Association of body round index with chronic kidney disease: a population-based cross-sectional study from NHANES 1999-2018.International urology and nephrology · 2025Article
- Obesity Medication Treatment Perspectives Among People with Overweight or Obesity.Patient preference and adherence · 2025Article
- Exploring Adiposity and Chronic Kidney Disease: Clinical Implications, Management Strategies, Prognostic Considerations.Medicina (Kaunas, Lithuania) · 2024Review
- Prevalence and associations of chronic kidney disease among antiretroviral therapy-naïve persons living with HIV in Lagos, Nigeria.BMC nephrology · 2024Article
- The risk of herpes zoster is positively associated with obesity, especially morbid obesity.Scientific reports · 2024Article
- Prevalence of Chronic Kidney Disease in a High-Risk Population in Urban Lahore, Pakistan: A Cross-sectional Study.Cureus · 2024Article
- Obesity-related renal dysfunction: gender-specific influence of visceral adiposity and early impact of metabolic and bariatric surgery.Frontiers in endocrinology · 2024Article
- The Effect of Metabolic Syndrome and Its Individual Components on Renal Function: A Meta-Analysis.Journal of clinical medicine · 2023Review
- Irisin protects against obesity-related chronic kidney disease by regulating perirenal adipose tissue function in obese mice.Lipids in health and disease · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic kidney disease (CKD) is one of the main chronic diseases affecting the world population due to its high prevalence and increasing morbidity. Similarly, obesity gained the interest of the scientific community as it directly or indirectly increases mortality from cardiovascular causes, and its prevalence characterizes a pandemic. The objective of this study was to investigate obesity measured by body mass index as a predictor for end-stage renal disease in the general adult population. A systematic review and meta-analysis was carried out by searching 10 databases for prospective or retrospective cohort studies, with no restrictions on the language of publication, including adults with obesity without previous renal disease and who evolved to CKD (diagnosed by estimated glomerular filtration rate below 60 mL&mac_middot;min-1&mac_middot;(1.73 m2)-1 over the follow-up period. The R software and Meta package were used for data analysis. After removing duplicates, 5431 studies were submitted to the steps of the systematic review, and 21 articles were included in the data analysis. In total, 3,504,303 patients, 521,216 with obesity, and an average follow-up time of 9.86 years were included. The relative risk of obese people for developing CKD in the random effects model was 1.81 (95%CI: 1.52-2.16). The evidence found in this meta-analysis confirmed that obese people are at higher risk of developing CKD that the non-obese population (1.81 times higher), with obesity being a priority risk factor in preventive actions.
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