Evidence map›Paper›PMID 33655883›Full record

ArticleeLife2021

A mobile genetic element increases bacterial host fitness by manipulating development.

Joshua M Jones, Ilana Grinberg, Avigdor Eldar, Alan D Grossman

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
7.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Clinical and molecular epidemiology ofFrontiers in microbiology · 2026
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  6. The TIGER/Islander resource for genomic islands.Microbiology resource announcements · 2025
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  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. The metabolic burden associated with plasmid acquisition: An assessment of the unrecognized benefits to host cells.BioEssays : news and reviews in molecular, cellular and developmental biology · 2025
    Review
  13. Characterization of High-Linezolid-MICInfection and drug resistance · 2025
    Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Joshua M JonesDepartment of Biology, Massachusetts Institute of Technology, Cambridge, United States.ORCID 0000-0002-3327-8899
Ilana GrinbergThe Shmunis School of Biomedicine and Cancer Research, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.
Avigdor EldarThe Shmunis School of Biomedicine and Cancer Research, Faculty of Life Sciences, Tel Aviv University, Tel Aviv, Israel.ORCID 0000-0001-8485-9370
Alan D GrossmanDepartment of Biology, Massachusetts Institute of Technology, Cambridge, United States.ORCID 0000-0002-8235-7227
Massachusetts Institute of Technology · USTel Aviv University · IL

Funding

QUORUM SENSING AND GENE EXPRESSION IN BACILLUS SUBTILISR01GM050895 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GROSSMAN, ALAN D · 1994 to 2017
$5.6M
Mechanisms and regulation of replication, the cell cycle, gene expression, and horizontal gene transfer in prokaryotes, focusing on Bacillus subtilisR35GM122538 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI GROSSMAN, ALAN D · 2017 to 2021
$3.2M
NIGMS NIH HHS R01 GM050895NIGMS NIH HHS R35 GM122538
6 · The paper itself

Abstract

Horizontal gene transfer is a major force in bacterial evolution. Mobile genetic elements are responsible for much of horizontal gene transfer and also carry beneficial cargo genes. Uncovering strategies used by mobile genetic elements to benefit host cells is crucial for understanding their stability and spread in populations. We describe a benefit that ICE

Indexed as

Genetic FitnessGene Transfer, HorizontalBacillus subtilisDNA, BacterialHost Microbial InteractionsInterspersed Repetitive SequencesDNA, BacterialbiofilmsB. subtilishorizontal gene transferinfectious diseaseintegrative and conjugative elements (ICE)microbial developmentmicrobiologymobile genetic elementssporulation

Identifiers

PMID33655883
PMCPMC8032392
OpenAlexW3135059624

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.