Evidence map›Paper›PMID 33655760›Full record

ArticleAmerican journal of physiology. Gastrointestinal and liver physiology2021

Estimation of mechanical work done to open the esophagogastric junction using functional lumen imaging probe panometry.

Shashank Acharya, Sourav Halder, Dustin A Carlson, Wenjun Kou, Peter J Kahrilas, John E Pandolfino, Neelesh A Patankar

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in American journal of physiology. Gastrointestinal and liver physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06883175 (Evolution of the Chicago Classification), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06883175 narecruitingnot on this mapstarted 2024, after this paper: background citation

Evolution of the Chicago Classification: Bridging Physiology and Mechanics

TypeinterventionalSponsorNorthwestern UniversityRan2024 to 2029Enrolled575ConditionsDysphagia, Achalasia, Esophageal, Ineffective Esophageal MotilityArmsFLIP, HRM, Prucalopride
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shashank AcharyaDepartment of Mechanical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois.ORCID 0000-0001-5341-1792
Sourav HalderTheoretical and Applied Mechanics Program, McCormick School of Engineering, Northwestern University, Evanston, Illinois.ORCID 0000-0002-8366-8860
Dustin A CarlsonDivision of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Wenjun KouDivision of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Peter J KahrilasDivision of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
John E PandolfinoDivision of Gastroenterology and Hepatology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois.
Neelesh A PatankarDepartment of Mechanical Engineering, McCormick School of Engineering, Northwestern University, Evanston, Illinois.ORCID 0000-0002-0665-3454
Northwestern University · US

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Role of altered response to volumetric distension in esophageal diseaseP01DK117824 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2018 to 2022
$7.3M
The mechanics of symptom generation in dysphagiaR01DK079902 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI PANDOLFINO, JOHN E · 2009 to 2017
$2.9M
NCATS NIH HHS UL1 TR001422NIDDK NIH HHS P01 DK117824NIDDK NIH HHS R01 DK079902
6 · The paper itself

Abstract

In this study, we quantify the work done by the esophagus to open the esophagogastric junction (EGJ) and create a passage for bolus flow into the stomach. Work done on the EGJ was computed using functional lumen imaging probe (FLIP) panometry. Eighty-five individuals underwent FLIP panometry with a 16-cm catheter during sedated endoscopy including asymptomatic controls (

Indexed as

AdultAgedEosinophilic EsophagitisEsophageal AchalasiaEsophagogastric JunctionEsophagusFemaleGastric EmptyingGastroesophageal RefluxHumansMaleManometryMiddle AgedYoung Adultdistension-induced EGJ relaxationenergyLES and EGJ openingmechanical workpressure-volume work

Identifiers

PMID33655760
PMCPMC8202198
OpenAlexW3133619528

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.