Evidence map›Paper›PMID 33655718›Full record

ArticleESC heart failure2021

Differential effect of malnutrition between patients hospitalized with new-onset heart failure and worsening of chronic heart failure.

Koichiro Matsumura, Wakana Teranaka, Masanao Taniichi, Munemitsu Otagaki, Hiroki Takahashi, Kenichi Fujii, Yoshihiro Yamamoto, Gaku Nakazawa, Ichiro Shiojima

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ESC heart failure, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. [The value of the nutritional assessment index or score in prognostic evaluation for patients with liver cancer].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2026
    Review
  4. Article
  5. Article
  6. Observational
  7. Diet in Scleroderma: Is There a Need for Intervention?Diagnostics (Basel, Switzerland) · 2021
    Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Koichiro MatsumuraDepartment of Cardiology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, 5708507, Japan.ORCID 0000-0002-9089-3505
Wakana TeranakaDepartment of Cardiology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, 5708507, Japan.
Masanao TaniichiDepartment of Cardiology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, 5708507, Japan.
Munemitsu OtagakiDepartment of Cardiology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, 5708507, Japan.
Hiroki TakahashiDepartment of Cardiology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, 5708507, Japan.
Kenichi FujiiDepartment of Cardiology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, 5708507, Japan.
Yoshihiro YamamotoDepartment of Cardiology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, 5708507, Japan.
Gaku NakazawaDepartment of Cardiology, Kindai University, 377-2, Ohno-higashi, Osakasayama, 5898511, Japan.
Ichiro ShiojimaDepartment of Cardiology, Kansai Medical University, 10-15, Fumizono-cho, Moriguchi, 5708507, Japan.
Kansai Medical University · JPKindai University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsWe aimed to investigate the differences in the prevalence, severity, and prognostic impact of malnutrition between patients with new-onset heart failure (HF) and worsening of chronic HF. METHODS AND

resultsIn older (≥60 years) hospitalized patients with acute HF, malnutrition was assessed according to the Geriatric Nutritional Risk Index (GNRI). A score <92 was defined as malnutrition. The primary endpoint was a composite endpoint, including cardiac death or rehospitalization for HF. Among 210 patients, 37% (52/142) of patients with new-onset HF and 31% (21/68) of patients with worsening of chronic HF had malnutrition (P = 0.41). The GNRI classification was comparable between the two groups. Kaplan-Meier analysis revealed a significant difference in the incidence of the composite endpoint in patients with new-onset HF (GNRI < 92 vs. GNRI ≥ 92: 50% vs. 32%, P = 0.007), but not in patients with worsening of chronic HF (GNRI < 92 vs. GNRI ≥ 92: 67% vs. 68%, P = 0.91). The adjusted Cox proportional hazards model demonstrated that a GNRI of <92 was an independent prognostic factor for the composite endpoint in patients with new-onset HF only.

conclusionsAmong older hospitalized patients with acute HF, the prevalence and severity of malnutrition were comparable between the two categories of patients. Malnutrition was an independent prognostic factor in patients with new-onset HF, while clinical prognosis was poor in patients with worsening of HF, irrespective of malnutrition. The prognostic impact of malnutrition differs between new-onset HF and worsening of chronic HF.

Indexed as

Heart FailureMalnutritionAgedHumansNutritional StatusNutrition AssessmentPrognosisAcute heart failureGeriatric Nutritional Risk IndexNew-onset heart failureWorsening of chronic heart failure

Identifiers

PMID33655718
PMCPMC8120416
OpenAlexW3134944074

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.