ReviewJournal of cosmetic dermatology2021
The impact of ultraviolet radiation on skin photoaging - review of in vitro studies.
Review in Journal of cosmetic dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07722351 (Instrumental Assessment of a Homocysteic Acid-containing Chemical Skin Biostimulator in the Management of Photoaged Mature Skin), which is not on this map. Cited by 122 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Instrumental Assessment of a Homocysteic Acid-containing Chemical Skin Biostimulator in the Management of Photoaged Mature Skin
Who cites it
122 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Quercetin as a therapeutic agent for skin problems: a systematic review and meta-analysis on antioxidant effects, oxidative stress, inflammation, wound healing, hyperpigmentation, aging, and skin cancer.Naunyn-Schmiedeberg's archives of pharmacology · 2025Pooled it
- The Tiny Big Difference: Nanotechnology in Photoprotective Innovations - A Systematic Review.AAPS PharmSciTech · 2024Pooled it
- Prospective, Randomized, Double-Blind, Placebo-Controlled Study of an Oral Antioxidant-Rich Synbiotic Supplement on Skin Health and Photoaging.Journal of cosmetic dermatology · 2026Trial
- Dietary Supplement With Cherry Blossom Flower and Rosa roxburghii Tratt Fruit Extract Improves Skin Aging: A Randomized, Placebo-Controlled, Blinded Clinical Study.Journal of cosmetic dermatology · 2025Trial
- Efficacy of combined 1927 nm thulium fiber laser and supramolecular salicylic acid in photoaging treatment.Lasers in medical science · 2025Trial
- A Randomized, Single-Center, Double-Blind, Controlled Case Study Evaluating Procedure Pairing of a Neurocosmetic Postprocedure Cream With Radiofrequency Microneedling for Facial Rejuvenation.Journal of cosmetic dermatology · 2024Trial
- Skin Rejuvenation Efficacy and Safety Evaluation ofBiomolecules · 2024Trial
- Protein Post-Translational Modifications in UV-Induced Skin Damage.Experimental dermatology · 2026Review
- Protective Effects of Duchesnea chrysantha Ethanol Extract Against UVB-Induced Skin Damage via Modulation of TAK1-Associated Signaling Pathways.Chemistry & biodiversity · 2026Article
- Protective Effects of a Mixture of Propolis andInternational journal of molecular sciences · 2026Article
- Instrumental Assessment of a Chemical Skin Biostimulator Combining Ammonium Trichloroacetate and Homocysteic Acid in Photoaged Mature Skin: A Single-Arm Prospective Study.Molecules (Basel, Switzerland) · 2026Article
- Food-Medicine Homologous Qiongyu Gao Attenuates Skin Photoaging by Remodeling Gut Microbiota and Restoring Mitochondrial Energy Metabolism.Foods (Basel, Switzerland) · 2026Article
- Article
- Topical Tinospora cordifolia BSA Hydrogel Formulation Attenuates UVB-Induced Skin Inflammation in Golden Hamsters.Chemistry & biodiversity · 2026Article
- Hydroxytyrosol Improves UV-Induced Skin Photoaging via PI3K-AKT/MAPK/JAK-STAT and NF-κB Pathways: Insights From Keratinocytes and In Vivo Validation.Phytotherapy research : PTR · 2026Article
- V-ATPase-targeted siRNA library screening reveals ATP6V1A negatively regulates UVB-induced keratinocyte senescence.Biology direct · 2026Article
- Alpha-Ketoglutarate Attenuates UVB-Induced Skin Photoaging by Restoring Mitochondrial Redox Homeostasis.Antioxidants (Basel, Switzerland) · 2026Article
- Sulforaphane as a Photoprotective Agent Against UV-Induced Skin Damage and Carcinogenesis: A Scoping Review.Journal of personalized medicine · 2026Review
- Antiaging Effects of Mannose-6-Phosphate through Enhanced Mitochondrial Function and Collagen Remodeling.ACS omega · 2026Article
- Chitosan-based nanozyme hydrogels: Advanced antioxidant and sustained-release systems for the prevention and treatment of skin photoaging.International journal of pharmaceutics: X · 2026Review
62 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPhotoaging, ultra violet (UV) induced skin aging is a gradual process that depends on the time and intensity of solar radiation.
aimThe aim of this paper was to review of the literature focused on in vitro studies explaining the mechanisms of photoaging.
methodsElectronic databases, including PubMed and MEDLINE, were searched for in vitro studies on the importance of UV radiation in the skin photoaging process of peer-reviewed scientific journals. Only articles available in English and full version publications were considered for this review.
resultsThree main modes of UV radiation action on skin cells which lead to photoaging, there are changes in cell metabolism, induction of oxidative stress due to the change in enzyme activity.
conclusionThe information gathered in this publication will help to better understand the complex and multidirectional mechanism of skin photoaging, which will contribute to the development of research on potential cosmetic products that provide effective and safe sun protection or repair damage caused by UV radiation.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.