Evidence map›Paper›PMID 33655487›Full record

Observational studyActa anaesthesiologica Scandinavica2021

Two-months quality of life of COVID-19 invasively ventilated survivors; an Italian single-center study.

Giacomo Monti, Carlo Leggieri, Evgeny Fominskiy, Anna Mara Scandroglio, Sergio Colombo, Margherita Tozzi, Elena Moizo, Milena Mucci, Martina Crivellari, Marina Pieri and 13 more

Open access · bronzeAbstract readObservational Study
In one paragraph

Observational study in Acta anaesthesiologica Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 9 pooled it
6.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 9 syntheses or guidelines pooled it, 51 citations in OpenAlex.

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  5. COVID-19 associated cognitive impairment: A systematic review.Cortex; a journal devoted to the study of the nervous system and behavior · 2022
    Pooled it
  6. Clinical patterns of somatic symptoms in patients suffering from post-acute long COVID: a systematic review.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2022
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  12. Italian Technostress Creators Scale: Validation of an Assessment Tool.Journal of occupational and environmental medicine · 2025
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  19. COVID-19 Oral Sequelae: Persistent Gustatory and Saliva Secretory Dysfunctions after Recovery from COVID-19.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 1 institution in 1 country.

Giacomo MontiDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Carlo LeggieriDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Evgeny FominskiyDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Anna Mara ScandroglioDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Sergio ColomboDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Margherita TozziDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Elena MoizoDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Milena MucciDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Martina CrivellariDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Marina PieriDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Francesca GuzzoDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Simona PiemonteseIRCCS San Raffaele Scientific Institute, Hematology and Bone Marrow Transplant Unit, Milan, Italy.
Rebecca De LorenzoDepartment of Internal Medicine, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Valentina Da PratGeneral Medicine and Advanced Care Unit, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Monica FedrizziDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Carolina FaustiniDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Martina Di PiazzaDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Francesca ConteDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Rosalba LemboDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Antonio EspositoIRCCS San Raffaele Scientific Institute, Clinical and Experimental Radiology Unit, Experimental Imaging Centre, Milan, Italy.
Lorenzo DagnaIRCCS San Raffaele Scientific Institute, Medicine and Clinical Immunology, Milan, Italy.
Giovanni LandoniDepartment of Anaesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.ORCID 0000-0002-8594-5980
Alberto ZangrilloVita-Salute University San Raffaele, Milano, Italia, Anesthesia and Intensive Care, Milan, Italy.
Vita-Salute San Raffaele University · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCOVID-19 disease can lead to severe functional impairments after discharge. We assessed the quality of life of invasively ventilated COVID-19 ARDS survivors.

methodsWe carried out a prospective follow-up study of the patients admitted to the Intensive Care Units (ICUs) of a teaching hospital. Patients affected by COVID-19 ARDS who required invasive ventilation and were successfully discharged home were assessed through the telephone administration of validated tests. We explored survival, functional outcomes, return to work, quality of life, cognitive and psychological sequelae. The main variables of interest were the following: demographics, severity scores, laboratory values, comorbidities, schooling, working status, treatments received during ICU stay, complications, and psychological, cognitive, functional outcomes.

resultsOut of 116 consecutive invasively ventilated patients, overall survival was 65/116 (56%) with no death occurring after hospital discharge. Forty-two patients were already discharged home with a median follow-up time of 61 (51-71) days after ICU discharge and 39 of them accepted to be interviewed. Only one patient (1/39) experienced cognitive decline. The vast majority of patients reported no difficulty in walking (32/35:82%), self-care (33/39:85%), and usual activities (30/39:78%). All patients were either malnourished (15/39:38%) or at risk for malnutrition (24/39:62%). Exertional dyspnea was present in 20/39 (51%) patients. 19/39 (49%) reported alterations in senses of smell and/or taste either before or after hospitalization.

conclusionsInvasively ventilated COVID-19 ARDS survivors have an overall good recovery at a 2-months follow-up which is better than what was previously reported in non-COVID-19 ARDS patients.

Indexed as

Quality of LifeRecovery of FunctionCOVID-19Critical CareFemaleFollow-Up StudiesHumansItalyMaleMalnutritionMiddle AgedProspective StudiesRespiration, ArtificialSurveys and QuestionnairesSurvivorsAcute respiratory distress syndromeCOVID-19critically ill patientsfollow-upintensive carequality-of-life

Identifiers

PMID33655487
PMCPMC8014684
OpenAlexW3133582833

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.