ArticleAnnals of intensive care2021
Continuous positive airway pressure for respiratory support during COVID-19 pandemic: a frugal approach from bench to bedside.
Article in Annals of intensive care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 32 citations in OpenAlex.
- High-Dose Dexamethasone and Oxygen Support Strategies in Intensive Care Unit Patients With Severe COVID-19 Acute Hypoxemic Respiratory Failure: The COVIDICUS Randomized Clinical Trial.JAMA internal medicine · 2022Trial
- A clinical guide to non-invasive respiratory support in acute respiratory failure: ventilation settings, technical optimization and clinical indications.Critical care (London, England) · 2025Review
- Advanced non-invasive respiratory support in resource-constrained settings: a narrative review.Critical care (London, England) · 2025Review
- Noninvasive ventilation in acute hypoxemic respiratory failure: What is the future?Journal of intensive medicine · 2025Review
- Impact of circuit configuration on the mechanical performance of CPAP therapy devices: an experimental study.Frontiers in medical technology · 2025Article
- High flow nasal cannula and low level continuous positive airway pressure have different physiological effects during de novo acute hypoxemic respiratory failure.Annals of intensive care · 2024Article
- Modeling ventilation of patients with interstitial lung disease at rest and exercise: a bench study.BMC pulmonary medicine · 2024Article
- Oxygen therapy and noninvasive respiratory supports in acute hypoxemic respiratory failure: a narrative review.Annals of intensive care · 2024Review
- Article
- A new reservoir-based CPAP with low oxygen consumption: the Bag-CPAP.Critical care (London, England) · 2023Article
- Dual titration of minute ventilation and sweep gas flow to control carbon dioxide variations in patients on venovenous extracorporeal membrane oxygenation.Annals of intensive care · 2023Article
- Technical Innovation in Critical Care in a World of Constraints: Lessons from the COVID-19 Pandemic.American journal of respiratory and critical care medicine · 2023Article
- Acute Improvements of Oxygenation with Cpap and Clinical Outcomes in Severe COVID-19 Pneumonia: A Multicenter, Retrospective Study.Journal of clinical medicine · 2022Article
- Observational
- The oxygenation module: the missing link in using sleep apnea devices to treat COVID-19 pneumonia at home.Biomedical engineering online · 2022Article
- Noninvasive respiratory support for acute respiratory failure due to COVID-19.Current opinion in critical care · 2022Review
- Non-invasive respiratory support in the management of acute COVID-19 pneumonia: considerations for clinical practice and priorities for research.The Lancet. Respiratory medicine · 2022Review
- Feedback of inter-hospital transfer of patients under high-flow nasal cannula oxygen therapy.World journal of emergency medicine · 2022Article
- Interhospital transport of patients with COVID-19 under high-flow nasal cannula (HFNC).The American journal of emergency medicine · 2021Article
- Patient-Self Inflicted Lung Injury: A Practical Review.Journal of clinical medicine · 2021Review
Corrections and comments
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Authors and funding
29 authors at 7 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe describe a frugal approach (focusing on needs, performance, and costs) to manage a massive influx of COVID-19 patients with acute hypoxemic respiratory failure (AHRF) using the Boussignac valve protected by a filter ("Filter Frugal CPAP", FF-CPAP) in and out the ICU.
methods(1) A bench study measured the impact of two filters with different mechanical properties on CPAP performances, and pressures were also measured in patients. (2) Non-ICU healthcare staff working in COVID-19 intermediate care units were trained with a video tutorial posted on a massive open online course. (3) A clinical study assessed the feasibility and safety of using FF-CPAP to maintain oxygenation and manage patients out of the ICU during a massive outbreak.
resultsBench assessments showed that adding a filter did not affect the effective pressure delivered to the patient. The resistive load induced by the filter variably increased the simulated patient's work of breathing (6-34%) needed to sustain the tidal volume, depending on the filter's resistance, respiratory mechanics and basal inspiratory effort. In patients, FF-CPAP achieved pressures similar to those obtained on the bench. The massive training tool provided precious information on the use of Boussignac FF-CPAP on COVID-19 patients. Then 85 COVID-19 patients with ICU admission criteria over a 1-month period were studied upon FF-CPAP initiation for AHRF. FF-CPAP significantly decreased respiratory rate and increased SpO
conclusionAdding a filter to the Boussignac valve does not affect the delivered pressure but may variably increase the resistive load depending on the filter used. Clinical assessment suggests that FF-CPAP is a frugal solution to provide a ventilatory support and improve oxygenation to numerous patients suffering from AHRF in the context of a massive outbreak.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.