Evidence map›Paper›PMID 33655385›Full record

ArticleJournal of general internal medicine2022

NIH Funding, Research Productivity, and Scientific Impact: a 20-Year Study.

Rajiv Agarwal, Wanzhu Tu

Abstract read
In one paragraph

Article in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Productivity of National Cancer Institute K Awardees and Their Transition to Independent Funding.Journal of cancer education : the official journal of the American Association for Cancer Education · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rajiv AgarwalDivision of Nephrology, Department of Medicine, Indiana University School of Medicine and Richard L. Roudebush Veterans Administration Medical Center, 1481 West 10th Street, Indianapolis, IN, USA. ragarwal@iu.edu.ORCID 0000-0001-8355-7100
Wanzhu TuDepartment of Biostatistics, Indiana University Center for Aging Research, Indiana University School of Medicine, Indianapolis, IN, USA.

Funding

Integrated Therapies for Alcohol use in Alcohol-associated Liver Disease (ITAALD) - Indiana University Data Coordinating CenterU24AA026969 · NIAAA · INDIANA UNIVERSITY INDIANAPOLIS · PI SAMER GAWRIEH, WANZHU TU · 2018 to 2026
$20.2M
ChLorthalidone In Chronic Kidney Disease (CLICK) StudyR01HL126903 · NHLBI · INDIANA UNIVERSITY INDIANAPOLIS · PI AGARWAL, RAJIV · 2016 to 2020
$3.2M
Mechanisms of erythropoietin induced hypertensionI01CX001753 · VA · RLR VA MEDICAL CENTER · PI AGARWAL, RAJIV · 2019 to 2023
–
CSRD VA I01 CX001753NHLBI NIH HHS R01 HL126903NIAAA NIH HHS U24 AA026969NIH HHS U24AA026969VA I01CX001753
6 · The paper itself

Abstract

backgroundThe Research Project Grant (R01) is the oldest grant mechanism used by the National Institutes of Health (NIH). Receiving an R01 award is often taken as a sign of scientific success. We presented normative data on multiple productivity and impact metrics for a more objective assessment of funded grants' scientific success.

methodsAll initial R01 grants awarded by NIH in the year 2000 were prospectively followed and evaluated using the numbers of publications and citations, as well as the h-indices at the grant level. We examined the variability, time trends, and relations among these metrics to better understand the funded projects' cumulative output and impact.

resultsIn the 20 years since initial funding, 4451 R01 grants generated a total of 55,053 publications. These publications were cumulatively cited 3,705,553 times over 736,811 citation years. The median number of publications was 8 (25

conclusionNumbers of publications, citations, and h-indices vary greatly among funded R01 grants. When used together, these metrics provide a more complete picture of the productivity and long-term impact of a funded grant.

Indexed as

Awards and PrizesBiomedical ResearchFinancing, OrganizedHumansNational Institutes of Health (U.S.)United Statesh-indexNIH grantsresearch productivity

Identifiers

PMID33655385
PMCPMC8738817

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.