Evidence map›Paper›PMID 33655329›Full record

ArticleInternational journal of oncology2021

Ingredients such as trehalose and hesperidin taken as supplements or foods reverse alterations in human T cells, reducing asbestos exposure-induced antitumor immunity.

Shoko Yamamoto, Suni Lee, Toshio Ariyasu, Shin Endo, Satomi Miyata, Akiko Yasuda, Akira Harashima, Tsunetaka Ohta, Naoko Kumagai-Τakei, Tatsuo Ito and 5 more

Open access · hybridAbstract read
In one paragraph

Article in International journal of oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Shoko YamamotoDepartment of Hygiene, Kawasaki Medical School, Kurashiki, Okayama 701-0192, Japan.
Suni LeeDepartment of Hygiene, Kawasaki Medical School, Kurashiki, Okayama 701-0192, Japan.
Toshio AriyasuR&D Division, Hayashibara Co., Ltd., Naka-ku, Okayama 702-8006, Japan.
Shin EndoR&D Division, Hayashibara Co., Ltd., Naka-ku, Okayama 702-8006, Japan.
Satomi MiyataR&D Division, Hayashibara Co., Ltd., Naka-ku, Okayama 702-8006, Japan.
Akiko YasudaR&D Division, Hayashibara Co., Ltd., Naka-ku, Okayama 702-8006, Japan.
Akira HarashimaR&D Division, Hayashibara Co., Ltd., Naka-ku, Okayama 702-8006, Japan.
Tsunetaka OhtaR&D Division, Hayashibara Co., Ltd., Naka-ku, Okayama 702-8006, Japan.
Naoko Kumagai-ΤakeiDepartment of Hygiene, Kawasaki Medical School, Kurashiki, Okayama 701-0192, Japan.
Tatsuo ItoDepartment of Hygiene, Kawasaki Medical School, Kurashiki, Okayama 701-0192, Japan.
Yurika ShimizuDepartment of Pathophysiology-Periodontal Science, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Kita-ku, Okayama 700-0867, Japan.
Bandaru SrinivasDepartment of Hygiene, Kawasaki Medical School, Kurashiki, Okayama 701-0192, Japan.
Nagisa SadaDepartment of Hygiene, Kawasaki Medical School, Kurashiki, Okayama 701-0192, Japan.
Yasumitsu NishimuraDepartment of Hygiene, Kawasaki Medical School, Kurashiki, Okayama 701-0192, Japan.
Takemi OtsukiDepartment of Hygiene, Kawasaki Medical School, Kurashiki, Okayama 701-0192, Japan.
Kawasaki Medical School · JPHayashibara (Japan) · JPOkayama University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Exposure of human immune cells to asbestos causes a reduction in antitumor immunity. The present study aimed to investigate the recovery of reduced antitumor immunity by several ingredients taken as supplements or foods, including trehalose (Treh) and glycosylated hesperidin (gHesp). Peripheral blood CD4

Indexed as

Dietary SupplementsAsbestosCD4-Positive T-LymphocytesCells, CulturedHesperidinHumansInterferon-gammaInterleukin-17MaleMesothelioma, MalignantMiddle AgedReceptors, CXCR3TrehaloseAsbestosHesperidinIL17A protein, humanInterferon-gammaInterleukin-17Receptors, CXCR3Trehaloseantitumor immunityasbestoshesperidinT celltrehalose

Identifiers

PMID33655329
PMCPMC7891817
OpenAlexW3126306018

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.