Evidence map›Paper›PMID 33655067›Full record

ArticleACS central science2021

Specialized Metabolites Reveal Evolutionary History and Geographic Dispersion of a Multilateral Symbiosis.

Taise T H Fukuda, Eric J N Helfrich, Emily Mevers, Weilan G P Melo, Ethan B Van Arnam, David R Andes, Cameron R Currie, Monica T Pupo, Jon Clardy

Abstract read
In one paragraph

Article in ACS central science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Why Do FilamentousAnnual review of microbiology · 2025
    Review
  5. Fatuamide A, a Hybrid PKS/NRPS Metallophore from aJournal of natural products · 2025
    Article
  6. Article
  7. How host species and body part determine the microbial communities of five ambrosia beetle species.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Applied and environmental microbiology · 2023
    Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Taise T H FukudaDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States.
Eric J N HelfrichDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States.
Emily MeversDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States.
Weilan G P MeloSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo 14040-903, Brazil.
Ethan B Van ArnamDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States.
David R AndesDepartment of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53705, United States.
Cameron R CurrieDepartment of Bacteriology, University of Wisconsin-Madison, Madison, Wisconsin 53706, United States.
Monica T PupoSchool of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, São Paulo 14040-903, Brazil.
Jon ClardyDepartment of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, United States.

Funding

Novel therapeutic agents from the bacterial symbionts of Brazilian invertebratesU19TW009872 · FIC · HARVARD MEDICAL SCHOOL · PI CLARDY, JON, PUPO, MONICA T · 2014 to 2018
$4.4M
Chemical biology of bacterial symbiontsR01AT009874 · NCCIH · HARVARD MEDICAL SCHOOL · PI CLARDY, JON · 2017 to 2019
$1.2M
FIC NIH HHS U19 TW009872NCCIH NIH HHS R01 AT009874
6 · The paper itself

Abstract

Fungus-growing ants engage in a multilateral symbiosis: they cultivate a fungal garden as their primary food source and host symbiotic actinobacteria (

Identifiers

PMID33655067
PMCPMC7908033

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.