Evidence map›Paper›PMID 33655008›Full record

ArticleBio-protocol2019

Evaluation of Mucosal and Systemic Vaccine Responses by Cyclic di-GMP (CDG)-adjuvanted Protein Subunit Vaccines.

Samira Mansouri, Lei Jin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bio-protocol, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Samira MansouriDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL, USA.
Lei JinDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL, USA.

Funding

Mechanisms of STING-Mediated Mucosal Vaccine Adjuvant Activity of Cyclic di-GMPR01AI110606 · NIAID · UNIVERSITY OF FLORIDA · PI JIN, LEI · 2015 to 2019
$1.3M
Impact of Human STING Variants on Pneumococcal Vaccine EffectivenessR21AI125999 · NIAID · UNIVERSITY OF FLORIDA · PI JIN, LEI · 2016 to 2017
$413k
NIAID NIH HHS R01 AI110606NIAID NIH HHS R21 AI125999
6 · The paper itself

Abstract

Intranasal administration of vaccine adjuvants directly deliver therapeutic agents to the lungs to induce potent lung mucosal immune responses. Cyclic di-GMP (CDG) is a promising mucosal vaccine adjuvant candidate capable of inducing protective immunity. This protocol describes an

Indexed as

Cyclic dinucleotidesEx vivo recall assayHumoral and cellular vaccine responsesIntranasal immunizationMucosal vaccine adjuvant

Identifiers

PMID33655008
PMCPMC7854200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.