Evidence map›Paper›PMID 33654990›Full record

ArticleBio-protocol2019

Differentiation of Human Induced Pluripotent Stem Cells (iPSCs) into an Effective Model of Forebrain Neural Progenitor Cells and Mature Neurons.

Scott Bell, Nuwan C Hettige, Heika Silveira, Huashan Peng, Hanrong Wu, Malvin Jefri, Lilit Antonyan, Ying Zhang, Xin Zhang, Carl Ernst

Open access · bronzeAbstract read
In one paragraph

Article in Bio-protocol, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.

  1. Pooled it
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  16. Cell transplantation to repair the injured spinal cord.International review of neurobiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Scott BellPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Nuwan C HettigePsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Heika SilveiraPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Huashan PengPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Hanrong WuPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Malvin JefriPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Lilit AntonyanPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Ying ZhangPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Xin ZhangPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Carl ErnstPsychiatric Genetics Group, McGill University and Douglas Hospital Research Institute, Department of Psychiatry, Verdun, Montreal, QC H4H 1R3, Canada.
Douglas Mental Health University Institute · CAMcGill University · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Induced Pluripotent Stem Cells (iPSCs) are pluripotent stem cells that can be generated from somatic cells, and provide a way to model the development of neural tissues

Indexed as

CorticalForebrainiPSCNeuronNPCNSC

Identifiers

PMID33654990
PMCPMC7854068
OpenAlexW2918325303

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.