ArticleQuantitative imaging in medicine and surgery2021
Optical imaging of stimulation-evoked cortical activity using GCaMP6f and jRGECO1a.
Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 14 citations in OpenAlex.
- Article
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- Mapping of neurovascular and neurometabolic couplings by multimodal optical imaging.Cerebral cortex (New York, N.Y. : 1991) · 2025Article
- Review of cocaine-induced brain vascular and cellular function changes measuredNeurophotonics · 2025Review
- Miniscope Imaging of Nucleus Accumbens Neural Activity in Freely Behaving Rats: Virus Injection, Gradient Index Lens Implantation, Recording Strategies, and Analytical Methods.Current protocols · 2025Article
- WidefieldNeurophotonics · 2024Article
- Astrocytes modulate cerebral blood flow and neuronal response to cocaine in prefrontal cortex.Molecular psychiatry · 2024Article
- Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2023Article
- Circuit Investigation of Social Interaction and Substance Use Disorder Using Miniscopes.Frontiers in neural circuits · 2021Review
- Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundGenetically encoded calcium indicators (GECIs), especially the GCaMP-based green fluorescence GECIs have been widely used for
methodsGCaMP6f and jRGECO1a GECI were virally delivered to sensory cortex. After 3-4 weeks, the animals were imaged to capture the spatiotemporal changes of neuronal Ca
resultsHistology confirmed that the efficiency of jRGECO1a and GCaMP6f expression into the cortical neurons was similar, i.e., 34%±3% and 32.7%±1.6%, respectively. Our imaging
conclusionsThis study shows that both jRGECO1a and GCaMP6f have sufficient sensitivity for tracking single-stimulation-evoked Ca
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.