Evidence map›Paper›PMID 33654399›Full record

ArticleNeuropsychiatric disease and treatment2021

Association Analysis Between Catechol-O-Methyltransferase Expression and Cognitive Function in Patients with Schizophrenia, Bipolar Disorder, or Major Depression.

Peiyan Ni, Manli Liu, Dequan Wang, Yang Tian, Liansheng Zhao, Jinxue Wei, Xueli Yu, Xueyu Qi, Xiaojing Li, Hua Yu and 6 more

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Peiyan NiThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Manli LiuThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Dequan WangThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.ORCID 0000-0002-2506-468X
Yang TianThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Liansheng ZhaoThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Jinxue WeiThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Xueli YuThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Xueyu QiThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.ORCID 0000-0002-0860-9289
Xiaojing LiThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Hua YuThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Rongjun NiThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Xiaohong MaThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Wei DengThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Wanjun GuoThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Qiang WangThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Tao LiThe Psychiatric Laboratory, West China Hospital, Sichuan University, Chengdu, 610041, People's Republic of China.
Sichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSchizophrenia, bipolar disorder (BD), and major depressive disorder are three common mental disorders. Although their diagnosis and treatment differ, they partially overlap.

methodsTo explore the similarities and characteristics of these three psychiatric diseases, an intelligence quotient (IQ) assessment was performed to evaluate cognitive deficits. Relative catechol-O-methyltransferase (

resultsThe results indicated that patients with any of the three psychiatric diseases presented IQ deficits, and that the first-episode schizophrenia (FES) group had even lower cognitive function than the other two groups. The relative

conclusionIn conclusion, this cross-disease strategy provided important clues to explain lower IQ scores and dysregulated

Indexed as

BDbipolar disordercatechol-O-methyltransferaseCOMTFESfirst-episode major depressive disorderfirst-episode schizophreniaintelligence quotientIQMDD

Identifiers

PMID33654399
PMCPMC7910219
OpenAlexW3132747979

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.