Evidence map›Paper›PMID 33654391›Full record

ArticleInternational journal of chronic obstructive pulmonary disease

Assessment of Ventilatory Heterogeneity in Chronic Obstructive Pulmonary Disease Using the Inspired Sinewave Test.

Richard M Bruce, Phi Anh Phan, Marzia Rigolli, Minh C Tran, Edmund Pacpaco, Najib M Rahman, Andrew D Farmery

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of chronic obstructive pulmonary disease. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Richard M BruceCentre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, King's College London, London, UK.ORCID 0000-0002-8941-3519
Phi Anh PhanNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
Marzia RigolliUniversity of Oxford Centre for Clinical Magnetic Resonance Research, University of Oxford, Oxford, UK.
Minh C TranNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.ORCID 0000-0003-2622-1365
Edmund PacpacoOxford University Hospitals NHS Foundation Trust, Oxford Centre for Respiratory Medicine, Oxford, UK.
Najib M RahmanOxford University Hospitals NHS Foundation Trust, Oxford Centre for Respiratory Medicine, Oxford, UK.ORCID 0000-0003-1195-1680
Andrew D FarmeryNuffield Department of Clinical Neurosciences, University of Oxford, Oxford, UK.
University of Oxford · GBOxford University Hospitals NHS Trust · GBKing's College London · GB

Funding

Department of Health II-LA-0214-20005Department of Health NIHR200029
6 · The paper itself

Abstract

backgroundThere is marked variability in the symptoms and outcomes of patients with chronic obstructive pulmonary disease (COPD) which are poorly predicted by spirometry/FEV MATERIALS AND

methodsThe inspired sinewave test (IST) sinusoidally modulates the inspired concentration of a tracer gas (N

resultsELV

conclusionThe IST indices of VH were superior and independent predictors of symptom severity vs FEV

Indexed as

Pulmonary Disease, Chronic ObstructiveDyspneaForced Expiratory VolumeHumansLungRespiratory Function TestsSpirometryCOPDlung function testmedical devicenitrous oxideventilatory heterogeneity

Identifiers

PMID33654391
PMCPMC7914067
OpenAlexW3130613887

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.