ReviewAnnals of gastroenterology2021
Flexible endoscopic treatment for Zenker's diverticulum: from the lumen to the third space.
Review in Annals of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- The role of peroral endoscopic myotomy for Zenker's diverticulum: a systematic review and meta-analysis.Surgical endoscopy · 2022Pooled it
- Zenker's diverticulum in the era of third-space endoscopy: innovations, challenges, and adverse event management.iGIE : innovation, investigation and insights · 2026Review
- Zenker's peroral endoscopic myotomy for treating zenker's diverticulum in an elderly patient: a case report and literature review.Frontiers in surgery · 2026Article
- Tissue Staplers in Transcervical Diverticulectomy - A Novel Approach to Closing Zenker's Diverticulum.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025Article
- Transoral septotomy versus Z-POEM in the treatment of Zenker diverticulum: a multicenter case-matched comparative study.Surgical endoscopy · 2025Article
- The Endoscopic Management of Zenker's Diverticulum: A Comprehensive Review.Diagnostics (Basel, Switzerland) · 2024Review
- [Interventional endoscopy in gastroenterology].Innere Medizin (Heidelberg, Germany) · 2023Article
- Review
- Third-space endoscopy: the final frontier.Gastroenterology report · 2023Review
- Article
- Peroral endoscopic myotomy (Z-POEM) versus flexible endoscopic septotomy (FES) for treatment of Zenker's diverticulum: does either make the cut? A systematic review and meta-analysis of outcomes.Annals of gastroenterologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Zenker's diverticulum (ZD) is a rare outpouching of the esophageal mucosa herniating posteriorly through Killian's triangle. Treatments of ZD aim to dissect the cricopharyngeal muscle to remove the underlying dysfunctional condition. In the last decade, a septotomy performed utilizing a flexible endoscope has been reported as a safe and effective alternative to both open surgery and rigid endoscopic diverticulotomy. More recently, Li et al described a novel endoscopic technique to treat ZD, named "submucosal tunneling endoscopic septum division", inspired by the peroral endoscopic myotomy (POEM) procedure developed for achalasia. Subsequently, the term Z-POEM was introduced and has become the most frequently used acronym to define the tunneling technique for ZD. This article describes the flexible therapeutic endoscopic strategies for treating ZD, including the novel third space approach, which seems to show promising potential in terms of clinical efficacy and safety.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.