Evidence map›Paper›PMID 33654276›Full record

ArticlePediatric research2022

Infantile hemangiomas β

Andrea Bassi, Cesare Filippeschi, Teresa Oranges, Chiara Caporalini, Alessandro Pini, Patrizia Nardini, Roberta Marie Gentile, Luca Filippi

Abstract read
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In one paragraph

Article in Pediatric research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Andrea BassiDepartment of Health Science, Dermatologic Division, Meyer Children Hospital, Florence, Italy.
Cesare FilippeschiDepartment of Health Science, Dermatologic Division, Meyer Children Hospital, Florence, Italy.
Teresa OrangesDepartment of Health Science, Dermatologic Division, Meyer Children Hospital, Florence, Italy.
Chiara CaporaliniDivision of Pathology, Children's Hospital A. Meyer-University of Florence, Florence, Italy.
Alessandro PiniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Patrizia NardiniDepartment of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
Roberta Marie GentileNeonatal Intensive Care Unit, Medical Surgical Fetal-Neonatal Department, "A. Meyer" University Children's Hospital, Florence, Italy.
Luca FilippiDepartment of Clinical and Experimental Medicine, Division of Neonatology and NICU, University of Pisa, Pisa, Italy. luca.filippi@unipi.it.ORCID http://orcid.org/0000-0001-5310-9147
Meyer Children's Hospital · ITUniversity of Florence · ITUniversity of Pisa · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPropranolol (antagonist of β

methodsFifteen samples of surgical biopsies were collected from patients with IH. Three were taken precociously from infants and then successfully treated with propranolol (responder group). Twelve were taken later, from residual lesions noncompletely responsive to propranolol (nonresponder group). A morphometrical analysis of the percentage of β

resultsWhile no difference was found in both β

conclusionsAlthough the number of biopsies is insufficient to draw definitive conclusions, and the different β-AR pattern may be theoretically explained by the different timing of samplings, this study suggests a possible correlation between β IMPACT: Propranolol (unselective antagonist of β

Indexed as

Adrenergic beta-AntagonistsHemangiomaHumansInfantPropranololReceptors, Adrenergic, beta-3Adrenergic beta-AntagonistsPropranololReceptors, Adrenergic, beta-3

Identifiers

PMID33654276
OpenAlexW3135571845

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.