Trial reportScientific reports2021
Accuracy of new Corvis ST parameters for detecting subclinical and clinical keratoconus eyes in a Chinese population.
Trial report in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Early Detection of Keratoconus: Diagnostic Advances and Their Impact on Visual Outcomes: A Systematic Review.Medicina (Kaunas, Lithuania) · 2025Pooled it
- Single-shot, depth-encoded multiplexed OCT for multi-spot tracking of induced transient corneal dynamics.Biomedical optics express · 2026Article
- Article
- Orthokeratology for stable mild-to-moderate keratoconus: a pilot study on safety and corneal remodeling via quantitative OCT analysis.International ophthalmology · 2026Article
- Proteomic Analysis of Human Corneal Keratocytes Reveals Mechanical Strain-Dependent Changes in Cellular Function.Investigative ophthalmology & visual science · 2026Article
- Intraocular pressure measurement in keratoconus: a narrative review.International journal of ophthalmology · 2026Review
- Enhancing the diagnostic precision of subclinical keratoconus by combining indices from Scheimpflug tomography, corneal biomechanics, and anterior segment optical coherence tomography.International journal of ophthalmology · 2026Article
- Corneal Biomechanics Before and After Descemet Membrane Endothelial Keratoplasty in Patients with Fuchs Endothelial Corneal Dystrophy.Clinical ophthalmology (Auckland, N.Z.) · 2026Article
- Analysis of astigmatism type influence onFrontiers in bioengineering and biotechnology · 2026Article
- Diurnal Variations in Anterior Segment Parameters in Different Grades of Patients With Keratoconus.Translational vision science & technology · 2025Article
- Early diagnosis of keratoconus using corneal biomechanics and OCT derived technologies.Eye and vision (London, England) · 2025Review
- Diurnal variations in corneal biomechanics in healthy young adults.BMC ophthalmology · 2025Article
- Strategies for Early Keratoconus Diagnosis: A Narrative Review of Evaluating Affordable and Effective Detection Techniques.Journal of clinical medicine · 2025Review
- Development and validation of the VAE-NT index: a novel biomechanical parameter for distinguishing subclinical corneal abnormalities.Frontiers in bioengineering and biotechnology · 2025Article
- Biomechanical changes following corneal crosslinking in keratoconus patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024Article
- Impacts and Correlations on Corneal Biomechanics, Corneal Optical Density and Intraocular Pressure after Cataract Surgery.Diagnostics (Basel, Switzerland) · 2024Article
- The Chinese keratoconus (CKC) cohort study.European journal of epidemiology · 2024Article
- Distinguishing subclinical from clinical keratoconus by corneal measurements.Frontiers in medicine · 2024Article
- Corneal biomechanics in normal and subclinical keratoconus eyes.BMC ophthalmology · 2023Article
- Detection ability of corneal biomechanical parameters for early diagnosis of ectasia.Eye (London, England) · 2023Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study aimed to compare the values of new corneal visualization Scheimpflug technology (Corvis ST) parameters in normal, subclinical keratoconus (SKC) and keratoconus (KC) eyes, and evaluate the diagnostic ability to distinguish SKC and KC eyes from normal eyes. One-hundred normal, 100 SKC and 100 KC eyes were included in the study. Corvis ST parameters containing dynamic corneal response parameters were measured by one ophthalmologist. The receiver operating characteristic curve was used to evaluate the diagnostic ability of new Corvis ST parameters. The new Corvis ST parameters in KC eyes were different from those in the control and SKC eyes after adjusting for IOP and CCT, and stiffness parameter at the first applanation (SP-A1) and Corvis biomechanical index (CBI) were significantly different between the control and SKC eyes (all P < 0.05). The parameter with the highest diagnostic efficiency was SP-A1 (Youden index = 0.40, AUC = 0.753), followed by CBI (Youden index = 0.38, AUC = 0.703), and Integrated Radius (Youden index = 0.33, AUC = 0.668) in diagnosing SKC from control eyes. New Corvis ST parameters in SKC eyes were significantly different from normal control and KC eyes, and could be considered to distinguish SKC and KC eyes from normal eyes.
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