ArticleScientific data2021
Compilation of longitudinal microbiota data and hospitalome from hematopoietic cell transplantation patients.
Article in Scientific data, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT05824689 (Exploratory Study of Fluoroquinolone Resistance for Patients Undergoing Autologous Hematopoietic Stem Cell), which is not on this map. Cited by 26 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Exploratory Study of Fluoroquinolone Resistance for Patients Undergoing Autologous Hematopoietic Stem Cell (HSC) Transplantation in the Treatment of Multiple Myeloma
Who cites it
26 citing papers in PubMed.
- Acidification-dependent suppression ofInfection and immunity · 2026Article
- Fluoroquinolone Prophylaxis Uncovers High Prevalence Rates of Fluoroquinolone-ResistantCancers · 2026Article
- Contact dependent suppression ofbioRxiv : the preprint server for biology · 2026Article
- Metabiosis underlies a microbiota permissive to Pseudomonadota and increases the risk of gut-borne bloodstream infection.bioRxiv : the preprint server for biology · 2026Article
- Scale reliant mixed effects models enhance microbiome data analysis.Microbiome · 2026Article
- Acidification-dependent suppression ofbioRxiv : the preprint server for biology · 2026Article
- DynaBiome: interpretable unsupervised learning of gut microbiome dysbiosis via temporal deep models.BMC bioinformatics · 2026Article
- Dietary intake of enrofloxacin promotes the spread of antibiotic resistance from food to simulated human gut.The ISME journal · 2026Article
- Uncertainty Modeling Outperforms Machine Learning for Microbiome Data Analysis.bioRxiv : the preprint server for biology · 2025Article
- Ecological management of the microbiota in patients with cancer.Nature reviews. Clinical oncology · 2025Review
- Scalable log-ratio lasso regression for enhanced microbial feature selection with FLORAL.Cell reports methods · 2024Article
- Review
- The meaning of oral bacteria in faeces.Nature microbiology · 2024Article
- Oral bacteria relative abundance in faeces increases due to gut microbiota depletion and is linked with patient outcomes.Nature microbiology · 2024Article
- The MTIST platform: a microbiome time series inference standardized test.Research square · 2024Article
- Data-driven prediction of colonization outcomes for complex microbial communities.Nature communications · 2024Article
- Enhanced Feature Selection for Microbiome Data using FLORAL: Scalable Log-ratio Lasso Regression.bioRxiv : the preprint server for biology · 2023Article
- The TaxUMAP atlas: Efficient display of large clinical microbiome data reveals ecological competition in protection against bacteremia.Cell host & microbe · 2023Article
- Article
- Protective Effect of Intestinal Blautia Against Neutropenic Fever in Allogeneic Transplant Recipients.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2022Article
Corrections and comments
- Erratum issued
Authors and funding
15 authors.
Funding
Abstract
The impact of the gut microbiota in human health is affected by several factors including its composition, drug administrations, therapeutic interventions and underlying diseases. Unfortunately, many human microbiota datasets available publicly were collected to study the impact of single variables, and typically consist of outpatients in cross-sectional studies, have small sample numbers and/or lack metadata to account for confounders. These limitations can complicate reusing the data for questions outside their original focus. Here, we provide comprehensive longitudinal patient dataset that overcomes those limitations: a collection of fecal microbiota compositions (>10,000 microbiota samples from >1,000 patients) and a rich description of the "hospitalome" experienced by the hosts, i.e., their drug exposures and other metadata from patients with cancer, hospitalized to receive allogeneic hematopoietic cell transplantation (allo-HCT) at a large cancer center in the United States. We present five examples of how to apply these data to address clinical and scientific questions on host-associated microbial communities.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.