Evidence map›Paper›PMID 33654101›Full record

ArticleNPJ vaccines2021

A CCHFV DNA vaccine protects against heterologous challenge and establishes GP38 as immunorelevant in mice.

John J Suschak, Joseph W Golden, Collin J Fitzpatrick, Charles J Shoemaker, Catherine V Badger, Connie S Schmaljohn, Aura R Garrison

Open access · goldAbstract read
In one paragraph

Article in NPJ vaccines, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

John J SuschakVirology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA. jjsuschak@gmail.com.ORCID http://orcid.org/0000-0002-2867-8265
Joseph W GoldenVirology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA.ORCID http://orcid.org/0000-0002-9709-313X
Collin J FitzpatrickVirology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA.ORCID http://orcid.org/0000-0002-9891-7727
Charles J ShoemakerDiagnostics Systems Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA.
Catherine V BadgerVirology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA.
Connie S SchmaljohnHeadquarters Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA.
Aura R GarrisonVirology Division, United States Army Medical Research Institute of Infectious Diseases, Fort Detrick, MD, USA. aura.r.garrison.civ@mail.mil.ORCID http://orcid.org/0000-0003-3034-6400
United States Army Medical Research Institute of Infectious Diseases · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne virus that causes severe hemorrhagic fever disease in humans. Currently, no licensed CCHF vaccines exist, and the protective epitopes remain unclear. Previously, we tested a DNA vaccine expressing the M-segment glycoprotein precursor gene of the laboratory CCHFV strain IbAr 10200 (CCHFV-M

Identifiers

PMID33654101
PMCPMC7925670
OpenAlexW3135712494

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.