Evidence map›Paper›PMID 33654082›Full record

ArticleNature communications2021

A novel art of continuous noninvasive blood pressure measurement.

Jürgen Fortin, Dorothea E Rogge, Christian Fellner, Doris Flotzinger, Julian Grond, Katja Lerche, Bernd Saugel

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 2 pooled it
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 2 syntheses or guidelines pooled it, 94 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Setting up an autonomic unit within the neurological department: a position statement of the European Federation of Autonomic Societies.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2026
    Article
  4. Review
  5. Review
  6. Intrinsic PPG-ECG Coupling for Accurate and Low-Power Blood Pressure Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  7. Article
  8. Remote Blood Pressure Monitoring: A Comprehensive Review.American journal of hypertension · 2026
    Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Noncontact respiratory monitoring during sleep: comparison of the touchless flow signal with respiratory inductance plethysmography flow (RIPJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Haemodynamic monitoring during noncardiac surgery: past, present, and future.Journal of clinical monitoring and computing · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Jürgen FortinCNSystems Medizintechnik GmbH, Reininghausstrasse 13, 8020, Graz, Austria. juergen.fortin@cnsystems.com.ORCID http://orcid.org/0000-0002-9958-1938
Dorothea E RoggeDepartment of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.
Christian FellnerCNSystems Medizintechnik GmbH, Reininghausstrasse 13, 8020, Graz, Austria.
Doris FlotzingerCNSystems Medizintechnik GmbH, Reininghausstrasse 13, 8020, Graz, Austria.
Julian GrondCNSystems Medizintechnik GmbH, Reininghausstrasse 13, 8020, Graz, Austria.
Katja LercheCNSystems Medizintechnik GmbH, Reininghausstrasse 13, 8020, Graz, Austria.
Bernd SaugelDepartment of Anesthesiology, Center of Anesthesiology and Intensive Care Medicine, University Medical Center Hamburg-Eppendorf, Martinistrasse 52, 20246, Hamburg, Germany.ORCID http://orcid.org/0000-0001-6619-0722
Universität Hamburg · DECicor (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wearable sensors to continuously measure blood pressure and derived cardiovascular variables have the potential to revolutionize patient monitoring. Current wearable methods analyzing time components (e.g., pulse transit time) still lack clinical accuracy, whereas existing technologies for direct blood pressure measurement are too bulky. Here we present an innovative art of continuous noninvasive hemodynamic monitoring (CNAP2GO). It directly measures blood pressure by using a volume control technique and could be used for small wearable sensors integrated in a finger-ring. As a software prototype, CNAP2GO showed excellent blood pressure measurement performance in comparison with invasive reference measurements in 46 patients having surgery. The resulting pulsatile blood pressure signal carries information to derive cardiac output and other hemodynamic variables. We show that CNAP2GO can self-calibrate and be miniaturized for wearable approaches. CNAP2GO potentially constitutes the breakthrough for wearable sensors for blood pressure and flow monitoring in both ambulatory and in-hospital clinical settings.

Indexed as

AdultAlgorithmsBlood PressureBlood Pressure DeterminationCalibrationFemaleHemodynamicsHumansMaleMiddle AgedMiniaturizationMonitoring, PhysiologicPulseSignal Processing, Computer-AssistedSoftwareYoung Adult

Identifiers

PMID33654082
PMCPMC7925606
OpenAlexW3133938350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.