Evidence map›Paper›PMID 33653959›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Transcriptional heterogeneity and tightly regulated changes in gene expression during

Haikel N Bogale, Tales V Pascini, Sachie Kanatani, Juliana M Sá, Thomas E Wellems, Photini Sinnis, Joel Vega-Rodríguez, David Serre

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 51 citations in OpenAlex.

  1. Review
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  5. MappingbioRxiv : the preprint server for biology · 2025
    Article
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  7. Article
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  9. Degradation of ribosomal RNA duringbioRxiv : the preprint server for biology · 2025
    Article
  10. Article
  11. Late sporogonic stages ofbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Single-cell analyses of polyclonalResearch square · 2024
    Article
  15. Late sporogonic stages ofFrontiers in cellular and infection microbiology · 2024
    Article
  16. Article
  17. AnPathogens and global health · 2023
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Haikel N BogaleInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201.ORCID 0000-0002-1907-788X
Tales V PasciniLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0001-8759-0362
Sachie KanataniDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.ORCID 0000-0002-7072-0447
Juliana M SáLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0003-3813-8104
Thomas E WellemsLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892; twellems@niaid.nih.gov dserre@som.umaryland.edu.ORCID 0000-0003-3899-8454
Photini SinnisDepartment of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205.ORCID 0000-0003-2954-7547
Joel Vega-RodríguezLaboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-9576-0058
David SerreInstitute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD 21201; twellems@niaid.nih.gov dserre@som.umaryland.edu.
National Institutes of Health · USJohns Hopkins University · USUniversity of Maryland, Baltimore · US

Funding

Technology CoreU19AI110820 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI WHITE, OWEN R · 2014 to 2023
$36.5M
Malaria Drug Resistance and Disease VirulenceZIAAI000483 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI WELLEMS, THOMAS E · 2009 to 2025
$24.5M
EXPAND PARTICIPATION BY MINORITIES IN BIOMEDICAL SCIENCER25GM055036 · NIGMS · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI SUMMERS, MICHAEL FINLEY · 1996 to 2021
$16.9M
Host-parasite-vector interactions during malaria transmissionZIAAI001250 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI VEGA-RODRIGUEZ, JOEL · 2019 to 2025
$9.9M
The Skin Phase of Malaria Infection (Sharon Patray Diversity Supplement)R01AI132359 · NIAID · JOHNS HOPKINS UNIVERSITY · PI SINNIS, PHOTINI · 2017 to 2021
$2.7M
Are all sporozoites equal? Analyses of transcriptomes from individual Plasmodium sporozoites using single cell RNA-seqR21AI143932 · NIAID · UNIVERSITY OF MARYLAND BALTIMORE · PI SERRE, DAVID · 2019 to 2020
$441k
Intramural NIH HHS ZIA AI000483NIAID NIH HHS R01 AI132359NIAID NIH HHS R21 AI143932NIAID NIH HHS U19 AI110820NIGMS NIH HHS R25 GM055036
6 · The paper itself

Abstract

Despite the critical role of

Indexed as

Gene Expression RegulationTranscription, GeneticAnimalsAnophelesMicePlasmodium bergheiSalivary GlandsSporozoitesgene expressionmalariasingle-cell analysis

Identifiers

PMID33653959
PMCPMC7958459
OpenAlexW3134159989

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.