ArticlemBio2021
Open access · goldAbstract read
In one paragraph
Article in mBio, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 192 papers, 2 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
192citing papers in PubMed, 2 pooled it
14.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
192 citing papers in PubMed, 2 syntheses or guidelines pooled it, 246 citations in OpenAlex.
- Exploring the Diagnostic and Predictive Value of Oral Microbiome in Esophageal Cancer: A Systematic Review and Meta-Analysis.International journal of molecular sciences · 2025Pooled it
- A systematic review on omics data (metagenomics, metatranscriptomics, and metabolomics) in the role of microbiome in gallbladder disease.Frontiers in physiology · 2022Pooled it
- Probiotic treatment induces changes in intestinal microbiota but does not alter SCFA levels in peritoneal dialysis patients-a randomized, placebo-controlled trial.Scientific reports · 2024Trial
- An oral-gut microbial metabolite linksGut microbes · 2026Article
- Review
- The microbiota-proteostasis axis: implications in neurodegenerative diseases.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2026Review
- Huanglian-Wendan Decoction alleviates DSS-induced colitis by modulating the gut microbiota and protecting against intestinal injury via suppression of colonic apoptosis and endoplasmic reticulum stress.Natural products and bioprospecting · 2026Article
- New insights into outer membrane vesicles in Gram-negative bacteria from biogenesis to applications.Communications biology · 2026Review
- Bacterial extracellular vesicles modulate epithelial antiviral responses via macrophage-mediated immunomodulation.Cell communication and signaling : CCS · 2026Article
- Emerging signal transduction pathways and the role of bacterial extracellular vesicles linked to the pathogenesis of endometriosis.Communications medicine · 2026Review
- Helicobacter pylori-derived outer membrane vesicles: Pathogenic roles, microbiota interactions, and biomedical applications.Journal of advanced research · 2026Review
- Fusobacterium nucleatum in cancer: Interactions with microbiota, tumour colonisation and cancer progression.Clinical and translational medicine · 2026Review
- Screening and dynamic change study of microbial and metabolite markers for calf diarrhea based on multi-omics and machine learning.mSystems · 2026Article
- The Role of Oral Pathobionts' Outer Membrane Vesicles in Cancer Pathology and Therapeutic Development.Cells · 2026Review
- Pathogenic Roles ofPathogens (Basel, Switzerland) · 2026Review
- Effects of low-dose dietary antimicrobial peptide Scy-hepc on disease resistance in Larimichthys crocea under secondary infection.BMC microbiology · 2026Article
- Periodontitis and Chronic Liver Disease: Mechanistic Insights Focusing onMicroorganisms · 2026Review
- Review
- Exploring microorganism-host interactions: Emerging organoid models and analytical approaches.mLife · 2026Review
- Harnessing Microbiome-Mediated and Macrophage-Driven Mechanisms for Oral Wound Healing.Microorganisms · 2026Review
132 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors at 6 institutions in 1 country.
Melinda A EngevikDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA melinda.engevik@bcm.edu.ORCID 0000-0002-9742-9932
Heather A DanhofDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-6347-0021
Wenly RuanDepartment of Pediatrics, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-0391-5543
Amy C EngevikDepartment of Surgical Sciences, Vanderbilt University Medical Center, Nashville Tennessee, USA.ORCID 0000-0001-9108-3240
Alexandra L Chang-GrahamDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-3403-6787
Kristen A EngevikDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0001-9807-1875
Zhongcheng ShiDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0001-9267-4536
Yanling ZhaoDepartment of Pediatrics, Texas Children's Cancer Center, Texas Children's Hospital, Houston, Texas, USA.
Colleen K BrandDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0003-3866-2897
Evan S KrystofiakDepartment of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA.ORCID 0000-0002-0043-6977
Susan VenableDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0001-8752-1092
Xinli LiuDepartment of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, USA.
Kendal D HirschiDepartment of Pediatrics and Human and Molecular Genetics, Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-8498-7636
Joseph M HyserDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.
Jennifer K SpinlerDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-7830-7665
Robert A BrittonDepartment of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0001-8983-9539
James VersalovicDepartment of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.ORCID 0000-0002-5765-4385
Baylor College of Medicine · USChildren's Nutrition Research Center at Baylor College of Medicine · USTexas Children's Hospital · USUniversity of Houston · USVanderbilt University · USVanderbilt University Medical Center · US
Funding
Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STACIE B DUSETZINA · 1995 to 2026
$172.8MTranslational Analysis CoreP30DK058404 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI RICHARD M. PEEK · 2002 to 2026
$29.9MVanderbilt Diabetes Research CenterP30DK020593 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALVIN C POWERS · 2012 to 2026
$29.3MTissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI James Versalovic · 2001 to 2026
$28.3MShop Module CoreP30EY008126 · NEI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI David J. Calkins · 1989 to 2026
$19.6MVanderbilt Mouse Metabolic Physiology CenterU24DK059637 · NIDDK · VANDERBILT UNIVERSITY · PI WASSERMAN, DAVID H · 2001 to 2015
$14.9MProteomics CoreP30DK123704 · NIDDK · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI DON C. ROCKEY · 2020 to 2026
$8.8MResearch Training in Pediatrics GastroenterolgyT32DK007664 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI DOUGLAS G BURRIN · 1991 to 2026
$8.4MTraining Supplement in Enteric Virus Exploitation of Calcium SignalingR01DK115507 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Joseph M. Hyser · 2018 to 2026
$5.0MDiet driven evolution of epidemic ribotypes of Clostridium difficileR01AI123278 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI BRITTON, ROBERT A · 2018 to 2022
$2.0MSex, serotonin and visceral hypersensitivityR01DK103759 · NIDDK · MICHIGAN STATE UNIVERSITY · PI GALLIGAN, JAMES J. · 2015 to 2018
$1.3MThe role of Myosin Vb in Hepatocyte Protein TraffickingK01DK121869 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ENGEVIK, AMY C · 2019 to 2023
$669kNCI NIH HHS P30 CA068485NEI NIH HHS P30 EY008126NIAID NIH HHS F32 AI136404NIAID NIH HHS R01 AI123278NIDDK NIH HHS F30 DK112563NIDDK NIH HHS K01 DK121869NIDDK NIH HHS K01 DK123195NIDDK NIH HHS P30 DK020593NIDDK NIH HHS P30 DK056338NIDDK NIH HHS P30 DK058404NIDDK NIH HHS P30 DK123704NIDDK NIH HHS R01 DK103759NIDDK NIH HHS R01 DK115507NIDDK NIH HHS T32 DK007664NIDDK NIH HHS U24 DK059637
Abstract
Multiple studies have implicated microbes in the development of inflammation, but the mechanisms remain unknown. Bacteria in the genus
Indexed as
AnimalsBacterial Outer MembraneCells, CulturedColonCulture MediaCytokinesEpithelial CellsExtracellular VesiclesFemaleFusobacterium nucleatumGastrointestinal MicrobiomeHT29 CellsHumansInflammationIntestinesMaleCulture MediaCytokinesNF-kappa BToll-Like Receptor 4enteroidsepitheliumFusobacterium nucleatuminflammationintestinemicrobiomeorganoidsouter membrane vesiclesTLR4
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.