Evidence map›Paper›PMID 33653756›Full record

ArticleBMJ open2021

Mixed-method study to assess the feasibility, acceptability and early effectiveness of the Hospital to Home programme for follow-up of high-risk newborns in a rural district of Central Uganda: a study protocol.

Daniel Kabugo, Heidi Nakamura, Brooke Magnusson, Madeline Vaughan, Beatrice Niyonshaba, Cornety Nakiganda, Christine Otai, Kimber Haddix-McKay, Margaret Seela, Joyce Nankabala and 8 more

Open access · goldAbstract readClinical Trial Protocol
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 6 institutions in 4 countries.

Daniel Kabugo *Adara Development (Uganda), Adara Group, Nakaseke, Uganda.
Heidi Nakamura *Adara Development (USA), Adara Group, Edmonds, Washington, USA.
Brooke Magnusson *Adara Development (USA), Adara Group, Edmonds, Washington, USA.
Madeline Vaughan *Adara Development (Australia), Adara Group, Sydney, New South Wales, Australia.
Beatrice NiyonshabaAdara Development (Uganda), Adara Group, Nakaseke, Uganda.
Cornety NakigandaAdara Development (Uganda), Adara Group, Nakaseke, Uganda.
Christine OtaiAdara Development (Uganda), Adara Group, Nakaseke, Uganda.
Kimber Haddix-McKayAdara Development (USA), Adara Group, Edmonds, Washington, USA.
Margaret SeelaKiwoko Hospital, Kiwoko, Uganda.
Joyce NankabalaKiwoko Hospital, Kiwoko, Uganda.
Josephine NakakandeKiwoko Hospital, Kiwoko, Uganda.
Moses SsekiddeKiwoko Hospital, Kiwoko, Uganda.
Cally J TannDepartment of Infectious Disease Epidemiology, London School of Hygiene and Tropical Medicine, London, UK.
Benjamin J S Al-HaddadDivision of Neonatology, Department of Pediatrics, University of Washington, Seattle, Washington, USA.
James NyonyintonoKiwoko Hospital, Kiwoko, Uganda.
Paul MubiriSchool of Public Health, Makerere University, College of Health Sciences, Kampala, Uganda.
Peter WaiswaDepartment of Health Policy Planning and Management, Makerere University School of Public Health, Kampala, Uganda.
Mohan Paudel *Adara Development (Australia), Adara Group, Sydney, New South Wales, Australia mohan.paudel@adaragroup.org.ORCID http://orcid.org/0000-0002-4620-5197
Kiwoko Hospital · UGKarolinska Institutet · SEMakerere University · UGUniversity College London Hospitals NHS Foundation Trust · GBUniversity of Montana · USUniversity of Washington · US

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008244 · NIGMS · UNIVERSITY OF MINNESOTA TWIN CITIES · PI SHIMIZU, YOJI · 1988 to 2024
$13.6M
Medical Research Council MC_UP_1204/9NIGMS NIH HHS T32 GM008244
6 · The paper itself

Abstract

introductionA follow-up programme designed for high-risk newborns discharged from inpatient newborn units in low-resource settings is imperative to ensure these newborns receive the healthiest possible start to life. We aim to assess the feasibility, acceptability and early outcomes of a discharge and follow-up programme, called Hospital to Home (H2H), in a neonatal unit in central Uganda. METHODS AND ANALYSIS: We will use a mixed-methods study design comparing a historical cohort and an intervention cohort of newborns and their caregivers admitted to a neonatal unit in Uganda. The study design includes two main components. The first component includes qualitative interviews (n=60 or until reaching saturation) with caregivers, community health workers called Village Health Team (VHT) members and neonatal unit staff. The second component assesses and compares outcomes between a prospective intervention cohort (n=100, born between July 2019 and September 2019) and a historical cohort (n=100, born between July 2018 and September 2018) of infants. The historical cohort will receive standard care while the intervention cohort will receive standard care plus the H2H intervention. The H2H intervention comprises training for healthcare workers on lactation, breast feeding and neurodevelopmentally supportive care, including cue-based feeding, and training to caregivers on recognition of danger signs and care of their high-risk infants. Infants and their families receive home visits until 6 months of age, or longer if necessary, by specially trained VHTs. Quantitative data will be analysed using descriptive statistics and regression analysis. All results will be stratified by cohort group. Qualitative data will be analysed guided by Braun and Clarke's thematic analysis technique. ETHICS AND DISSEMINATION: This study protocol was approved by the relevant Ugandan ethics committees. All participants will provide written informed consent. We will disseminate through peer-reviewed publications and key stakeholders and public engagement. TRIAL REGISTRATION NUMBER: ISRCTN51636372; Pre-result.

Indexed as

HospitalsFeasibility StudiesFemaleFollow-Up StudiesHumansInfantInfant, NewbornPregnancyProspective StudiesUgandacommunity child healthhealth policyneonatal intensive & critical carequality in health care

Identifiers

PMID33653756
PMCPMC7929893
OpenAlexW3134131060

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.