Evidence map›Paper›PMID 33653419›Full record

ReviewCell & bioscience2021

In respond to commensal bacteria: γδT cells play a pleiotropic role in tumor immunity.

Yongting Liu, Ying Han, Shan Zeng, Hong Shen

Open access · goldAbstract readReview
In one paragraph

Review in Cell & bioscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.4field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. [Research Progress on the Relationship between Intratumor Microbiota and Lung Cancer].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2025
    Review
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yongting LiuDepartment of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Ying HanDepartment of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Shan ZengDepartment of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China.
Hong ShenDepartment of Oncology, Xiangya Hospital, Central South University, Changsha, 410008, Hunan, China. hongshen2000@csu.edu.cn.ORCID http://orcid.org/0000-0003-0593-7268
Central South University · CN

Funding

China Cancer Elite Team Innovative Grant 201606National Key R & D Program of China 2018YFC1313300National Natural Science Foundation of China 81070362National Natural Science Foundation of China 81172470National Natural Science Foundation of China 81372629National Natural Science Foundation of China 81772627National Natural Science Foundation of China 81874073National Natural Science Foundation of China 81974384Nature Science Foundation of Hunan Province 2015JC3021Nature Science Foundation of Hunan Province 2016JC2037
6 · The paper itself

Abstract

γδT cells are a mixture of innate programming and acquired adaptability that bridge the adaptive and innate immune systems. γδT cells are mainly classified as tissue-resident Vδ1 or circulating Vδ2 γδT cells. In the tumor microenvironment, tumor immunity is influenced by the increased quantity and phenotype plasticity of γδT cells. Commensal bacteria are ubiquitous in the human body, and they have been confirmed to exist in various tumor tissues. With the participation of commensal bacteria, γδT cells maintain homeostasis and are activated to affect the development and progression of tumors. Here, we summarize the relationship between γδT cells and commensal bacteria, the potential protumor and antitumor effects underlying γδT cells, and the new developments in γδT cell-based tumor therapy which is expected to open new opportunities for tumor immunotherapy.

Indexed as

Antitumor effectsCommensal bacteriaImmunity therapyProtumor effectsΓδ T cells

Identifiers

PMID33653419
PMCPMC7927236
OpenAlexW3134285133

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.