Evidence map›Paper›PMID 33653306›Full record

ArticleBMC cancer2021

Real world duration of curative intent breast, colorectal, non-small cell lung, and prostate cancer treatment.

Selina K Wong, Jeremy Hamm, Aria Shokoohi, Colleen E McGahan, Cheryl Ho

Open access · goldAbstract read
In one paragraph

Article in BMC cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Selina K WongDepartment of Medical Oncology, BC Cancer, Vancouver, BC, Canada.
Jeremy HammDepartment of Cancer Surveillance and Outcomes, BC Cancer, Vancouver, BC, Canada.
Aria ShokoohiDepartment of Medical Oncology, BC Cancer, Vancouver, BC, Canada.
Colleen E McGahanDepartment of Cancer Surveillance and Outcomes, BC Cancer, Vancouver, BC, Canada.
Cheryl HoDepartment of Medical Oncology, BC Cancer, Vancouver, BC, Canada. cho@bccancer.bc.ca.ORCID http://orcid.org/0000-0002-5922-3984
BC Cancer Agency · CAUniversity of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdvances in curative treatment for breast, colorectal, NSCLC and prostate cancer have led to improvements in cancer survival. Cancer treatment and recovery time can vary depending on the recommended modalities and intensity of therapy. Our objective was to determine the current real world duration of curative treatments for the four common cancers.

methodsA retrospective review was completed of patients referred to BC Cancer from 2010 to 2016, ≤ 65 years old, newly diagnosed with stage I-III breast, colorectal, NSCLC or prostate cancer who received curative intent treatment. Information was collected on baseline characteristics, date of diagnosis, surgery, type, duration and intent of both radiotherapy and chemotherapy.

resultsIn total, 22,275 patients were included: 55.7% breast, 22.4% colorectal, 9.2% NSCLC, 12.7% prostate cancer. Stage I/II/III at diagnosis: breast 47.2/38.7/14.1%, colorectal 26.5/30.1/43.5%, NSCLC 46.5/18.1/35.4%, prostate 7.7/62.9/29.4%. Patients treated with definitive surgery only: breast 35.9%, colorectal 58%, NSCLC 52.2%, prostate 40.1%. The median duration of multimodality treatment was breast 24.6 weeks, colorectal 26.7 weeks, NSCLC 9.1 weeks, and prostate 6.0 weeks.

conclusionsApproximately half of patients who undergo curative cancer treatment require definitive radiotherapy or multimodality treatment. The median duration of therapy for the most commonly treated cancers ranged from 6.0-26.7 weeks. Multimodality curative treatment can be prolonged for selected cancers when accounting for the duration of adjuvant chemotherapy and radiotherapy and recovery time between modalities.

Indexed as

Breast NeoplasmsCarcinoma, Non-Small-Cell LungColorectal NeoplasmsCombined Modality TherapyFemaleHumansLung NeoplasmsMaleMiddle AgedNeoplasm StagingProstatic NeoplasmsRetrospective StudiesTime FactorsAdjuvantBreastColorectalFinancialMedical leaveTreatment durationWorkplace

Identifiers

PMID33653306
PMCPMC7923613
OpenAlexW3134010398

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.