ArticleBMC geriatrics2021
A community-based nurse-led medication self-management intervention in the improvement of medication adherence in older patients with multimorbidity: protocol for a randomised controlled trial.
Article in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.
- Selection and reporting of usual care comparators when designing primary care trials of complex health interventions: a systematic review.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025Pooled it
- Impact of Interventions on Medication Adherence in Patients With Coexisting Diabetes and Hypertension.Health expectations : an international journal of public participation in health care and health policy · 2024Pooled it
- Performance-Based Usability of Medication Adherence Technologies Among Older Adults With Diverse Capabilities: Quantitative Study.JMIR aging · 2026Article
- Article
- Factors Affecting Medication Adherence in Middle-Aged and Elderly Patients in China: A Cross-Sectional Study.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Impact of the Information-Motivation-Behavioral Skills Model Based Medication Literacy Intervention on Medication Self-Management Capacity in Stroke Patients: A Randomized Controlled Trial.Patient preference and adherence · 2025Article
- Medication Adherence and Its Influencing Factors in Postoperative Thyroid Cancer Patients: A Cross-Sectional Study.Nursing research and practice · 2025Article
- Tools to measure barriers to medication management capacity in older adults: a scoping review.BMC geriatrics · 2024Article
- Impact of nurse-led interprofessional work in older patients with heart failure and multimorbidity: A retrospective cohort study.American heart journal plus : cardiology research and practice · 2024Article
- Trajectories of Treatment Burden Among Primary Care Patients with Long-Term Conditions in Southern China: A Latent Class Growth Analysis.Risk management and healthcare policy · 2024Article
- Association between medication literacy and medication adherence and the mediating effect of self-efficacy in older people with multimorbidity.BMC geriatrics · 2023Article
- Health Literacy in Adults with Chronic Diseases in the Context of Community Health Nursing: A Scoping Review.Nursing reports (Pavia, Italy) · 2023Article
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundOlder patients suffering from multimorbidity are at high risk of medication nonadherence. It has been well established that self-management support is an effective strategy to enhance medication adherence for patients with chronic conditions. However, little is known about the effect of the medication self-management intervention in older patients with multimorbidity. This paper presents the protocol for a study that aims to evaluate the effectiveness of a nurse-led medication self-management intervention in improving medication adherence and health outcomes for community-dwelling older patients with multimorbidity.
methodsThe study protocol follows the recommendations of the Standard Protocol Items: Recommendations for Interventional Trials 2013 statement. This study is a multicentre, single-blind, two-arm randomised controlled trial. Older patients with multimorbidity will be recruited from three community health centres in Changsha, China. A total of 136 participants will be randomly allocated to receive usual care or usual care plus the medication self-management intervention. The intervention will be delivered by community nurses. The 6-week intervention includes three face-to-face education sessions and two weekly follow-up phone calls. Participants in the control group continue to receive all respects of usual care offered by community healthcare providers, including chronic disease management, drug prescription, referral to hospital specialists, health education and consultations regarding patients' diseases and treatments during centre visits. The primary outcome is medication adherence as measured by the 5-item Medication Adherence Report Scale. Secondary outcomes include medication self-management capacity (medication knowledge, medication beliefs, medication social support, medication skills, and medication self-efficacy), treatment experiences (medication treatment satisfaction and treatment burden), quality of life, and utilisation of healthcare services. All outcomes will be measured at baseline, immediately post-intervention, and at 3-month post-intervention. DISCUSSION: This study will provide evidence about the effectiveness of a medication self-management intervention, delivered by nurses, for older patients with multimorbidity and adherence problems. It is expected that the results of the study, if proven effective in improving patients' adherence and health outcomes, will provide evidence-based self-management support strategies for healthcare providers in routine chronic disease management in community settings.
trial registrationThe trial is registered at ChiCTR.org.cn ( ChiCTR2000030011 ; date February 19, 2020).
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