Evidence map›Paper›PMID 33653263›Full record

ArticleBMC anesthesiology2021

Heart rate variability-derived features based on deep neural network for distinguishing different anaesthesia states.

Jian Zhan, Zhuo-Xi Wu, Zhen-Xin Duan, Gui-Ying Yang, Zhi-Yong Du, Xiao-Hang Bao, Hong Li

Abstract read
In one paragraph

Article in BMC anesthesiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  10. Heart rate variability in anaesthesiology - narrative review.Anaesthesiology intensive therapy · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jian ZhanDepartment of Anaesthesiology, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Zhuo-Xi WuDepartment of Anaesthesiology, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Zhen-Xin DuanDepartment of Anaesthesiology, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Gui-Ying YangDepartment of Anaesthesiology, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Zhi-Yong DuDepartment of Anaesthesiology, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Xiao-Hang BaoDepartment of Anaesthesiology, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China.
Hong LiDepartment of Anaesthesiology, The Second Affiliated Hospital of Army Medical University, Chongqing, 400037, China. lh78553@163.com.ORCID 0000-0002-1338-0829

Funding

Clinical Research Project of Army Medical University No.CX2019LC114 and 2018JSLC0015National Key Research and Development Project 2018YFC0117200
6 · The paper itself

Abstract

backgroundEstimating the depth of anaesthesia (DoA) is critical in modern anaesthetic practice. Multiple DoA monitors based on electroencephalograms (EEGs) have been widely used for DoA monitoring; however, these monitors may be inaccurate under certain conditions. In this work, we hypothesize that heart rate variability (HRV)-derived features based on a deep neural network can distinguish different anaesthesia states, providing a secondary tool for DoA assessment.

methodsA novel method of distinguishing different anaesthesia states was developed based on four HRV-derived features in the time and frequency domain combined with a deep neural network. Four features were extracted from an electrocardiogram, including the HRV high-frequency power, low-frequency power, high-to-low-frequency power ratio, and sample entropy. Next, these features were used as inputs for the deep neural network, which utilized the expert assessment of consciousness level as the reference output. Finally, the deep neural network was compared with the logistic regression, support vector machine, and decision tree models. The datasets of 23 anaesthesia patients were used to assess the proposed method.

resultsThe accuracies of the four models, in distinguishing the anaesthesia states, were 86.2% (logistic regression), 87.5% (support vector machine), 87.2% (decision tree), and 90.1% (deep neural network). The accuracy of deep neural network was higher than those of the logistic regression (p < 0.05), support vector machine (p < 0.05), and decision tree (p < 0.05) approaches. Our method outperformed the logistic regression, support vector machine, and decision tree methods.

conclusionsThe incorporation of four HRV-derived features in the time and frequency domain and a deep neural network could accurately distinguish between different anaesthesia states; however, this study is a pilot feasibility study. The proposed method-with other evaluation methods, such as EEG-is expected to assist anaesthesiologists in the accurate evaluation of the DoA.

Indexed as

Neural Networks, ComputerAnesthesiaDecision TreesElectrocardiographyFemaleHeart RateHumansMaleMiddle AgedReproducibility of ResultsSupport Vector MachineDeep neural networkDepth of anaesthesiaDiscrete wavelet transformHeart rate variability

Identifiers

PMID33653263
PMCPMC7923817

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.