Evidence map›Paper›PMID 33653218›Full record

ArticleThe Journal of asthma : official journal of the Association for the Care of Asthma2022

Sex differences in the relationship of sleep-disordered breathing and asthma control among children with severe asthma.

Sigfus Gunnlaugsson, Kimberly F Greco, Carter R Petty, Gabriella C Sierra, Natalie P Stamatiadis, Christine Thayer, Adam G Hammond, Lauren M Giancola, Umakanth Katwa, Tregony Simoneau and 2 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of asthma : official journal of the Association for the Care of Asthma, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 57% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Observational
  2. Paediatric asthma and non-allergic comorbidities: A review of current risk and proposed mechanisms.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2022
    Review
  3. [The relationship between adenoid and tonsil hypertrophy and asthma in children and analysis of changes in asthma after adenotonsillectomy].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Sigfus GunnlaugssonDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Kimberly F GrecoInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, MA, USA.
Carter R PettyInstitutional Centers for Clinical and Translational Research, Boston Children's Hospital, Boston, MA, USA.
Gabriella C SierraDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Natalie P StamatiadisDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Christine ThayerDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Adam G HammondDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Lauren M GiancolaDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Umakanth KatwaDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Tregony SimoneauDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Sachin N BaxiDivision of Allergy and Immunology, Boston Children's Hospital, Boston, MA, USA.
Jonathan M GaffinDivision of Pulmonary Medicine, Boston Children's Hospital, Boston, MA, USA.
Boston Children's Hospital · USHarvard University · US

Funding

Indoor Air Quality and Respiratory Morbidity in School-Aged Children with Bronchopulmonary DysplasiaR01ES030100 · NIEHS · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2019 to 2023
$3.7M
School-based air pollution and asthma morbidity in Inner City School ChildrenK23AI106945 · NIAID · BOSTON CHILDREN'S HOSPITAL · PI GAFFIN, JONATHAN MARK · 2013 to 2017
$822k
NIAID NIH HHS K23 AI106945NIEHS NIH HHS R01 ES030100
6 · The paper itself

Abstract

objectiveChildren with severe asthma are underrepresented in studies of the relationship of sleep-disordered breathing (SDB) and asthma and little is known about sex differences of these relationships. We sought to determine the relationship of SDB with asthma control and lung function among boys and girls within a pediatric severe asthma cohort.

methodsPatients attending clinic visits at the Boston Children's Hospital Pediatric Severe Asthma Program completed the Pediatric Sleep Questionnaire (PSQ), Asthma Control Test (ACT) and Spirometry. The prevalence of SDB was defined as a PSQ score >0.33. We analyzed the association between PSQ score and both ACT score and spirometry values in mixed effect models, testing interactions for age and sex.

resultsAmong 37 subjects, mean age was 11.8 years (4.4) and 23 (62.2%) were male, the prevalence of SDB was 43.2% (16/37). Including all 80 observations, there was a moderate negative correlation between PSQ and ACT scores (r=-0.46,

conclusionsSDB is common among children with severe asthma. Among children with severe asthma, SDB in girls portends to significantly worse asthma control than boys. Supplemental data for this article is available online at https://doi.org/10.1080/02770903.2021.1897838.

Indexed as

AsthmaSleep Apnea SyndromesChildFemaleHumansMaleSex CharacteristicsSleepSurveys and QuestionnairesPediatric asthmaPediatric Sleep Questionnairesevere asthmasleep-disordered breathing

Identifiers

PMID33653218
PMCPMC8458465
OpenAlexW3134184524

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.