ArticleExperimental biology and medicine (Maywood, N.J.)2021
COMMD1 upregulation is involved in copper efflux from ischemic hearts.
Article in Experimental biology and medicine (Maywood, N.J.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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Who cites it
11 citing papers in PubMed, 16 citations in OpenAlex.
- Neutrophil extracellular traps delivering lactylated S100a9 aggravate neuronal cuproptosis by regulating Ttr/Commd1/Atp7b axis after traumatic brain injury.Redox biology · 2026Article
- The Yin and Yang of copper in cardiovascular health and disease.Molecular and cellular biochemistry · 2026Review
- Elevated COMMD1 Contributes to Cardiomyocyte Copper Efflux in Chronic Myocardial Ischemia: Insights From Rhesus Monkey.Cell proliferation · 2025Article
- Imbalance of Essential Metals in Traumatic Brain Injury and Its Possible Link with Disorders of Consciousness.International journal of molecular sciences · 2023Review
- COMMD proteins function and their regulating roles in tumors.Frontiers in oncology · 2023Review
- Dynamic regulation of HIF-1 signaling in the rhesus monkey heart after ischemic injury.BMC cardiovascular disorders · 2022Article
- Regulatory miRNAs in Cardiovascular and Alzheimer's Disease: A Focus on Copper.International journal of molecular sciences · 2022Review
- Dietary copper intake and risk of myocardial infarction in US adults: A propensity score-matched analysis.Frontiers in cardiovascular medicine · 2022Article
- Copper Preserves Vasculature Structure and Function by Protecting Endothelial Cells from Apoptosis in Ischemic Myocardium.Journal of cardiovascular translational research · 2021Article
- The Association of Suppressed Hypoxia-Inducible Factor-1 Transactivation of Angiogenesis With Defective Recovery From Cerebral Ischemic Injury in Aged Rats.Frontiers in aging neuroscience · 2021Article
- Disruption of COMMD1 accelerates diabetic atherosclerosis by promoting glycolysis.Diabetes & vascular disease researchArticle
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Copper depletion is associated with myocardial ischemic infarction, in which copper metabolism MURR domain 1 (COMMD1) is increased. The present study was undertaken to test the hypothesis that the elevated COMMD1 is responsible for copper loss from the ischemic myocardium, thus worsening myocardial ischemic injury. Mice (C57BL/6J) were subjected to left anterior descending coronary artery permanent ligation to induce myocardial ischemic infarction. In the ischemic myocardium, copper reduction was associated with a significant increase in the protein level of COMMD1. A tamoxifen-inducible, cardiomyocyte -specific
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Registered trials
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