Evidence map›Paper›PMID 33652975›Full record

ArticleCurrent oncology (Toronto, Ont.)2021

From Theory to Practice: Bone Health in Women with Early Breast Cancer Treated with Aromatase Inhibitors.

Leonor Vasconcelos de Matos, Leonor Fernandes, Maria Teresa Neves, Fátima Alves, Mafalda Baleiras, André Ferreira, Pedro Giesteira Cotovio, Tiago Dias Domingues, Mariana Malheiro, Ana Plácido and 2 more

Open access · goldAbstract read
In one paragraph

Article in Current oncology (Toronto, Ont.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Leonor Vasconcelos de MatosDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.ORCID 0000-0001-9568-238X
Leonor FernandesDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.ORCID 0000-0001-6655-0986
Maria Teresa NevesDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.ORCID 0000-0002-9891-8009
Fátima AlvesDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.
Mafalda BaleirasDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.
André FerreiraDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.
Pedro Giesteira CotovioCEAUL, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisbon, Portugal.ORCID 0000-0001-6724-899X
Tiago Dias DominguesCEAUL, Faculdade de Ciências, Universidade de Lisboa, 1749-016 Lisbon, Portugal.
Mariana MalheiroDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.
Ana PlácidoDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.
Maria Helena MirandaDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.
Ana MartinsDepartment of Medical Oncology, Hospital de São Francisco Xavier, Centro Hospitalar de Lisboa Ocidental, 1449-005 Lisbon, Portugal.
Centro Hospitalar de Lisboa Ocidental · PTUniversity of Lisbon · PTCUF Porto Hospital · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aromatase inhibitors (AI) are extensively used as adjuvant endocrine therapy in post-menopausal women with hormone receptor-positive early breast cancer (HR+ EBC), but their impact on bone health is not negligible. This work aimed to assess bone loss, fracture incidence, and risk factors associated with these events, as well as the prognostic influence of fractures. We have conducted a retrospective cohort study of women with HR+ EBC under adjuvant therapy with AI, during a 3-year period. Four-hundred-and-fifty-one eligible women were reviewed (median age 68 years). Median time under AI was 40 months. A fracture event occurred in 8.4%, mostly in the radium and femoral neck and in older women (mean 74 vs. 68 years,

Indexed as

Aromatase InhibitorsBreast NeoplasmsAgedBone DensityFemaleHumansNeoplasm Recurrence, LocalRetrospective StudiesAromatase Inhibitorsaromatase inhibitorsbreast cancerfractureosteoporosis

Identifiers

PMID33652975
PMCPMC8025750
OpenAlexW3133619901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.