Evidence map›Paper›PMID 33652915›Full record

ReviewNutrients2021

Nutrition and Rheumatoid Arthritis in the 'Omics' Era.

Manuela Cassotta, Tamara Y Forbes-Hernandez, Danila Cianciosi, Maria Elexpuru Zabaleta, Sandra Sumalla Cano, Irma Dominguez, Beatriz Bullon, Lucia Regolo, Josè Miguel Alvarez-Suarez, Francesca Giampieri and 1 more

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
5.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Manuela CassottaResearch Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.
Tamara Y Forbes-HernandezNutrition and Food Science Group, Department of Analytical and Food Chemistry, CITACA, CACTI, University of Vigo, 36310 Vigo, Spain.
Danila CianciosiDepartment of Clinical Sciences, Faculty of Medicine, Polytechnic University of Marche, 60131 Ancona, Italy.ORCID 0000-0002-8781-3535
Maria Elexpuru ZabaletaResearch Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.ORCID 0000-0003-2997-1049
Sandra Sumalla CanoResearch Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.
Irma DominguezResearch Group on Foods, Nutritional Biochemistry and Health, Universidad Europea del Atlántico, 39011 Santander, Spain.
Beatriz BullonDepartment of Periodontology, Dental School, University of Sevilla, 41004 Sevilla, Spain.
Lucia RegoloDepartment of Clinical Sciences, Faculty of Medicine, Polytechnic University of Marche, 60131 Ancona, Italy.ORCID 0000-0001-9432-0408
Josè Miguel Alvarez-SuarezAgroScience & Food Research Group, Universidad de Las Américas, Quito 170125, Ecuador.ORCID 0000-0001-8509-1498
Francesca GiampieriDepartment of Clinical Sciences, Faculty of Medicine, Polytechnic University of Marche, 60131 Ancona, Italy.
Maurizio BattinoDepartment of Clinical Sciences, Faculty of Medicine, Polytechnic University of Marche, 60131 Ancona, Italy.
Universidad Europea del Atlántico · ESMarche Polytechnic University · ITJiangsu University · CNKing Abdulaziz University · SAUniversidad de Sevilla · ESUniversidade de Vigo · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Modern high-throughput 'omics' science tools (including genomics, transcriptomics, proteomics, metabolomics and microbiomics) are currently being applied to nutritional sciences to unravel the fundamental processes of health effects ascribed to particular nutrients in humans and to contribute to more precise nutritional advice. Diet and food components are key environmental factors that interact with the genome, transcriptome, proteome, metabolome and the microbiota, and this life-long interplay defines health and diseases state of the individual. Rheumatoid arthritis (RA) is a chronic autoimmune disease featured by a systemic immune-inflammatory response, in genetically susceptible individuals exposed to environmental triggers, including diet. In recent years increasing evidences suggested that nutritional factors and gut microbiome have a central role in RA risk and progression. The aim of this review is to summarize the main and most recent applications of 'omics' technologies in human nutrition and in RA research, examining the possible influences of some nutrients and nutritional patterns on RA pathogenesis, following a nutrigenomics approach. The opportunities and challenges of novel 'omics technologies' in the exploration of new avenues in RA and nutritional research to prevent and manage RA will be also discussed.

Indexed as

Arthritis, RheumatoidComputational BiologyGene Expression ProfilingGenomicsHumansMetabolomicsMicrobiotaNutrigenomicsProteomicsdietmetabolomicsmicrobiomemicrobiomicsnutrigenomicsproteomicsrheumatoid arthritis

Identifiers

PMID33652915
PMCPMC7996781
OpenAlexW3134015701

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.