Evidence map›Paper›PMID 33652805›Full record

ArticleDiagnostics (Basel, Switzerland)2021

Prenatal Biochemical and Ultrasound Markers in COVID-19 Pregnant Patients: A Prospective Case-Control Study.

Stefano Cosma, Andrea Roberto Carosso, Fulvio Borella, Jessica Cusato, Marialuisa Bovetti, Federica Bevilacqua, Marco Carosso, Fiammetta Gervasoni, Andrea Sciarrone, Luca Marozio and 6 more

Open access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 3 institutions in 1 country.

Stefano CosmaGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-0563-0071
Andrea Roberto CarossoGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-7734-4499
Fulvio BorellaGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-8398-7557
Jessica CusatoLaboratory of Clinical Pharmacology and Pharmacogenetics, Amedeo di Savoia Hospital, Department of Medical Sciences, University of Turin, 10126 Turin, Italy.ORCID 0000-0003-1977-9694
Marialuisa BovettiGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.
Federica BevilacquaGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-8145-3671
Marco CarossoGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-8809-2293
Fiammetta GervasoniGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.
Andrea SciarroneObstetrics-Gynecological Ultrasound and Prenatal Diagnosis Unit, Department of Obstetrics and Gynecology, City of Health and Science, 10126 Turin, Italy.
Luca MarozioGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.
Alberto RevelliGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.ORCID 0000-0002-5797-3722
Alessandro RolfoDepartment of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.ORCID 0000-0001-6730-8067
Claudia FilippiniDepartment of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.
Valeria GhisettiLaboratory of Microbiology and Virology, Amedeo di Savoia Hospital, ASL 'Città di Torino', 10126 Turin, Italy.
Giovanni Di PerriUnit of Infectious Diseases, Amedeo di Savoia Hospital, Department of Medical Sciences, University of Turin, 10126 Turin, Italy.
Chiara BenedettoGynecology and Obstetrics 1, Department of Surgical Sciences, City of Health and Science, University of Turin, 10126 Turin, Italy.
University of Turin · ITOspedale Amedeo di Savoia · ITPiedmont Reference Center for Epidemiology and Cancer Prevention · IT

Funding

Università degli Studi di Torino --
6 · The paper itself

Abstract

This prospective observational study aimed to evaluate whether women with SARS-CoV-2 infection during the first trimester of pregnancy are at higher risk of noninvasive prenatal screening test alterations and/or of congenital fetal anomalies at the second-trimester fetal anatomy scan. Maternal symptoms were secondly investigated. The study was carried out on 12-week pregnant women admitted for noninvasive prenatal testing (16 April and 22 June 2020). The cohort had seromolecular tests for SARS-CoV-2, after which they were divided into a positive case group and a negative control group. Both groups had 20-week ultrasound screening. Seventeen out of the 164 women tested positive for SARS-CoV-2 (10.3%). There were no significant differences in mean nuchal translucency thickness or biochemical markers (pregnancy-associated plasma protein A, alpha-fetoprotein, human chorionic gonadotropin, unconjugated estriol) between cases and controls (

Indexed as

COVID-19fetal congenital anomaliesfetusfirst trimesternuchal translucencyprenatal screening testSARS-CoV-2vertical transmission

Identifiers

PMID33652805
PMCPMC7996827
OpenAlexW3133580502

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.