Evidence map›Paper›PMID 33652742›Full record

ArticleInternational journal of molecular sciences2021

Impressic Acid Ameliorates Atopic Dermatitis-Like Skin Lesions by Inhibiting ERK1/2-Mediated Phosphorylation of NF-κB and STAT1.

Jae Ho Choi, Gi Ho Lee, Sun Woo Jin, Ji Yeon Kim, Yong Pil Hwang, Eun Hee Han, Young Ho Kim, Hye Gwang Jeong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Brianolide fromBiomolecules · 2025
    Article
  3. Article
  4. Frontiers in pharmacology · 2025
    Article
  5. Article
  6. Anti-Inflammatory and Antiatopic Effects ofMolecules (Basel, Switzerland) · 2023
    Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Jae Ho ChoiCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Gi Ho LeeCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Sun Woo JinCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Ji Yeon KimCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Yong Pil HwangFisheries Promotion Division, Mokpo City, Jeollanamdo 58613, Korea.ORCID 0000-0002-0671-4181
Eun Hee HanDrug & Disease Target Research Team, Division of Bioconvergence Analysis, Korea Basic Science Institute (KBSI), Cheongju 28119, Korea.ORCID 0000-0002-0137-0156
Young Ho KimCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0002-7441-9459
Hye Gwang JeongCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.ORCID 0000-0002-8020-8914
Chungnam National University · KRKorea Basic Science Institute · KR

Funding

National Research Foundation of Korea (NRF) grant funded by the Korea government (MSIP) Nos. NRF-2020R1A2C1007764, NRF-2020R1I1A1A01055488
6 · The paper itself

Abstract

Impressic acid (IPA), a lupane-type triterpenoid from

Indexed as

AnimalsCell LineCytokinesDermatitis, AtopicHumansMaleMAP Kinase Signaling SystemMiceMice, Inbred BALB CNF-kappa BPhosphorylationSkinSTAT1 Transcription FactorTriterpenes3,11-dihydroxylup-20(29)-en-28-oic acidCytokinesNF-kappa BSTAT1 Transcription FactorTriterpenesatopic dermatitis-like skin lesionsIgEimpressic acidNF-κBTARC

Identifiers

PMID33652742
PMCPMC7956308
OpenAlexW3134476743

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.